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MOUSE:GAMT

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Gamt
Protein Name(s) Guanidinoacetate N-methyltransferase
External Links
UniProt O35969
EMBL AF015887
AF010499
AF010498
AK140688
AK158087
BC049233
CCDS CCDS35976.1
CCDS83728.1
PIR JC5664
RefSeq NP_001334048.1
NP_034385.1
SMR O35969
IntAct O35969
MINT O35969
STRING 10090.ENSMUSP00000101002
iPTMnet O35969
PhosphoSitePlus O35969
SwissPalm O35969
REPRODUCTION-2DPAGE IPI00742399
O35969
SWISS-2DPAGE O35969
jPOST O35969
MaxQB O35969
PaxDb O35969
PeptideAtlas O35969
PRIDE O35969
Ensembl ENSMUST00000020359
ENSMUST00000105363
GeneID 14431
KEGG mmu:14431
UCSC uc007gcj.2
uc011xio.1
CTD 2593
MGI MGI:1098221
eggNOG ENOG410ISNM
ENOG410XPX4
GeneTree ENSGT00390000018061
HOGENOM HOG000010290
InParanoid O35969
KO K00542
OMA NHFDGIL
OrthoDB 1297303at2759
PhylomeDB O35969
TreeFam TF328555
Reactome R-MMU-71288
UniPathway UPA00104
PRO PR:O35969
Proteomes UP000000589
Bgee ENSMUSG00000020150
Genevisible O35969
GO GO:0005737
GO:0005829
GO:0005902
GO:0005634
GO:0030731
GO:0042803
GO:0008757
GO:0009887
GO:0006601
GO:0040014
GO:0046498
GO:0046500
GO:0007283
InterPro IPR016550
IPR026480
IPR029063
PIRSF PIRSF009285
SUPFAM SSF53335
PROSITE PS51559

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006601

creatine biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q14353
ensembl:ENSP00000403536

P

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q14353
ensembl:ENSP00000403536

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0006601

creatine biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

P

Seeded From UniProt

acts_upstream_of_or_within

GO:0006601

creatine biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q14353

P

Seeded From UniProt

acts_upstream_of_or_within

GO:0007283

spermatogenesis

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

Seeded From UniProt

enables

GO:0008757

S-adenosylmethionine-dependent methyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0009887

animal organ morphogenesis

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

  • has_participant:(EMAPA:31476)

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

F

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q14353

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0040014

regulation of multicellular organism growth

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

Seeded From UniProt

enables

GO:0042803

protein homodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0046498

S-adenosylhomocysteine metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

P

Seeded From UniProt

acts_upstream_of_or_within

GO:0046500

S-adenosylmethionine metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

P

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q14353

F

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.2

F

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016550

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0006601

creatine biosynthetic process

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

Seeded From UniProt

involved_in

GO:0006601

creatine biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00104

P

Seeded From UniProt

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

part_of

GO:0005902

microvillus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0293

C

Seeded From UniProt

part_of

GO:0005829

cytosol

Reactome:R-MMU-9021976

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

involved_in

GO:0006601

creatine biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00104

P

Seeded From UniProt

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

part_of

GO:0005902

microvillus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0293

C

Seeded From UniProt

involved_in

GO:0006601

creatine biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q14353
ensembl:ENSP00000403536

P

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q14353
ensembl:ENSP00000403536

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0006601

creatine biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

P

Seeded From UniProt

acts_upstream_of_or_within

GO:0006601

creatine biosynthetic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q14353

P

Seeded From UniProt

acts_upstream_of_or_within

GO:0007283

spermatogenesis

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

Seeded From UniProt

enables

GO:0008757

S-adenosylmethionine-dependent methyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0009887

animal organ morphogenesis

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

  • has_participant:(EMAPA:31476)

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

F

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q14353

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0040014

regulation of multicellular organism growth

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

Seeded From UniProt

enables

GO:0042803

protein homodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0046498

S-adenosylhomocysteine metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

P

Seeded From UniProt

acts_upstream_of_or_within

GO:0046500

S-adenosylmethionine metabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2659

P

Seeded From UniProt

part_of

GO:0005829

cytosol

Reactome:R-MMU-9021976

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q14353

F

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.2

F

Seeded From UniProt

enables

GO:0030731

guanidinoacetate N-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016550

F

Seeded From UniProt

acts_upstream_of_or_within

GO:0006601

creatine biosynthetic process

PMID:15028668[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

MGI:MGI:3044282

P

Seeded From UniProt


edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Schmidt, A et al. (2004) Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency. Hum. Mol. Genet. 13 905-21 PubMed GONUTS page
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