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MOUSE:DNM1L
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Dnm1l (synonyms: Drp1) | |
Protein Name(s) | Dynamin-1-like protein
Dynamin family member proline-rich carboxyl-terminal domain less Dymple Dynamin-related protein 1 | |
External Links | ||
UniProt | Q8K1M6 | |
EMBL | AB079133 AK051443 AK080871 BC027538 BC040777 BC079635 CF914619 | |
CCDS | CCDS27984.1 CCDS70689.1 | |
RefSeq | NP_001021118.1 NP_001263269.1 NP_001263270.1 NP_690029.2 XP_006522694.1 | |
UniGene | Mm.218820 | |
ProteinModelPortal | Q8K1M6 | |
SMR | Q8K1M6 | |
BioGrid | 216417 | |
DIP | DIP-54818N | |
IntAct | Q8K1M6 | |
MINT | MINT-1858955 | |
ChEMBL | CHEMBL2331072 | |
iPTMnet | Q8K1M6 | |
PhosphoSitePlus | Q8K1M6 | |
PeptideAtlas | Q8K1M6 | |
PRIDE | Q8K1M6 | |
Ensembl | ENSMUST00000023477 ENSMUST00000115749 | |
GeneID | 74006 | |
KEGG | mmu:74006 | |
UCSC | uc007yij.2 uc007yik.2 uc007yim.2 uc007yin.2 uc007yio.2 | |
CTD | 10059 | |
MGI | MGI:1921256 | |
GeneTree | ENSGT00760000119213 | |
HOGENOM | HOG000161068 | |
HOVERGEN | HBG107833 | |
InParanoid | Q8K1M6 | |
KO | K17065 | |
OMA | GQEPTTG | |
OrthoDB | EOG091G02TQ | |
PhylomeDB | Q8K1M6 | |
TreeFam | TF352031 | |
Reactome | [www.reactome.org/content/detail/R-MMU-75153 R-MMU-75153] | |
PRO | PR:Q8K1M6 | |
Proteomes | UP000000589 | |
Bgee | ENSMUSG00000022789 | |
CleanEx | MM_DNM1L | |
ExpressionAtlas | Q8K1M6 | |
Genevisible | Q8K1M6 | |
GO | GO:0005903 GO:0030054 GO:0005905 GO:0005737 GO:0005829 GO:0005783 GO:0005794 GO:0000139 GO:0043231 GO:0016020 GO:0005874 GO:0015630 GO:0005741 GO:0005739 GO:0099073 GO:0048471 GO:0005777 GO:0043234 GO:0030672 GO:0005525 GO:0030742 GO:0003924 GO:0042802 GO:0008289 GO:0008017 GO:0042803 GO:0017137 GO:0031625 GO:0003374 GO:0006897 GO:0060047 GO:0048312 GO:0061025 GO:0000266 GO:0043653 GO:0090149 GO:0070584 GO:0007005 GO:0070266 GO:0016559 GO:0043065 GO:2001244 GO:0090141 GO:0050714 GO:0090200 GO:0051289 GO:0070585 GO:0051259 GO:1903578 GO:0010821 GO:1903146 GO:1900063 GO:0032459 GO:0001836 | |
Gene3D | 3.40.50.300 | |
InterPro | IPR030556 IPR000375 IPR001401 IPR019762 IPR022812 IPR030381 IPR003130 IPR020850 IPR027417 | |
PANTHER | PTHR11566 PTHR11566:SF127 | |
Pfam | PF01031 PF00350 PF02212 | |
PRINTS | PR00195 | |
SMART | SM00053 SM00302 | |
SUPFAM | SSF52540 | |
PROSITE | PS00410 PS51718 PS51388 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0008637 |
apoptotic mitochondrial changes |
ECO:0000314 |
P |
MOUSE DNM1L (DRP1) // Mdivi, a specific inhibitor for Drp1, inhibited Sene-induced mitochondrial fragmentation (Fig. 5A). |
complete | |||||
GO:0051882 |
mitochondrial depolarization |
ECO:0000314 |
P |
MOUSE DNM1L (DRP1) // Mdivi, a specific inhibitor for Drp1, inhibited Sene-induced mitochondrial depolarization (Fig. 5C-G). |
complete | |||||
involved_in |
GO:0060047 |
heart contraction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1900063 |
regulation of peroxisome organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010821 |
regulation of mitochondrion organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0000746) |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903578 |
regulation of ATP metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005903 |
brush border |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000584) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051259 |
protein complex oligomerization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000266 |
mitochondrial fission |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070266 |
necroptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016559 |
peroxisome fission |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005777 |
peroxisome |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003924 |
GTPase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0003374 |
dynamin family protein polymerization involved in mitochondrial fission |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000266 |
mitochondrial fission |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1903146 |
regulation of autophagy of mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002480309 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061025 |
membrane fusion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000170085 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048312 |
intracellular distribution of mitochondria |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002480309 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043653 |
mitochondrial fragmentation involved in apoptotic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002480309 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0031966 |
mitochondrial membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000170085 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000170013 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010821 |
regulation of mitochondrion organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1921256 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008637 |
apoptotic mitochondrial changes |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002480309 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008017 |
microtubule binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003392 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003392 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003924 |
GTPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000170013 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0003374 |
dynamin family protein polymerization involved in mitochondrial fission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000170085 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000266 |
mitochondrial fission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0026479 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:2001244 |
positive regulation of intrinsic apoptotic signaling pathway |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:2000302 |
positive regulation of synaptic vesicle exocytosis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1904666 |
regulation of ubiquitin protein ligase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:5312923 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1904579 |
cellular response to thapsigargin |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1903146 |
regulation of autophagy of mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:1900244 |
positive regulation of synaptic vesicle endocytosis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1900063 |
regulation of peroxisome organization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0099503 |
secretory vesicle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
colocalizes_with |
GO:0099073 |
mitochondrion-derived vesicle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0098835 |
presynaptic endocytic zone membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0090149 |
mitochondrial membrane fission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0090141 |
positive regulation of mitochondrial fission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0090141 |
positive regulation of mitochondrial fission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0070585 |
protein localization to mitochondrion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0070584 |
mitochondrion morphogenesis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0070584 |
mitochondrion morphogenesis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0070266 |
necroptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0061025 |
membrane fusion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0061003 |
positive regulation of dendritic spine morphogenesis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0051433 |
BH2 domain binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0051289 |
protein homotetramerization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0051260 |
protein homooligomerization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0051259 |
protein complex oligomerization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0050714 |
positive regulation of protein secretion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0048488 |
synaptic vesicle endocytosis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0048312 |
intracellular distribution of mitochondria |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0048312 |
intracellular distribution of mitochondria |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043653 |
mitochondrial fragmentation involved in apoptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0043653 |
mitochondrial fragmentation involved in apoptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0043065 |
positive regulation of apoptotic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0036466 |
synaptic vesicle recycling via endosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0032459 |
regulation of protein oligomerization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0031966 |
mitochondrial membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0031625 |
ubiquitin protein ligase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0030742 |
GTP-dependent protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0030672 |
synaptic vesicle membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0030276 |
clathrin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0017137 |
Rab GTPase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0016559 |
peroxisome fission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0010821 |
regulation of mitochondrion organization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0010637 |
negative regulation of mitochondrial fusion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0010468 |
regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:5312923 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007005 |
mitochondrion organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:5312923 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007005 |
mitochondrion organization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006816 |
calcium ion transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:5312923 |
P |
Seeded From UniProt |
complete | ||
colocalizes_with |
GO:0005905 |
clathrin-coated pit |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005874 |
microtubule |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
colocalizes_with |
GO:0005874 |
microtubule |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005777 |
peroxisome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005777 |
peroxisome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003924 |
GTPase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0003374 |
dynamin family protein polymerization involved in mitochondrial fission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0001836 |
release of cytochrome c from mitochondria |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0000266 |
mitochondrial fission |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0000057) |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000266 |
mitochondrial fission |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0000057) |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000266 |
mitochondrial fission |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0000139 |
Golgi membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620416 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:2001244 |
positive regulation of intrinsic apoptotic signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903146 |
regulation of autophagy of mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1900063 |
regulation of peroxisome organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0099073 |
mitochondrion-derived vesicle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090149 |
mitochondrial membrane fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090141 |
positive regulation of mitochondrial fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070584 |
mitochondrion morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070266 |
necroptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061025 |
membrane fusion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051289 |
protein homotetramerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051259 |
protein complex oligomerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050714 |
positive regulation of protein secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048312 |
intracellular distribution of mitochondria |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043653 |
mitochondrial fragmentation involved in apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043065 |
positive regulation of apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032459 |
regulation of protein oligomerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0031625 |
ubiquitin protein ligase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0030742 |
GTP-dependent protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0017137 |
Rab GTPase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0016559 |
peroxisome fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010821 |
regulation of mitochondrion organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007005 |
mitochondrion organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005874 |
microtubule |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005777 |
peroxisome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003924 |
GTPase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0003374 |
dynamin family protein polymerization involved in mitochondrial fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001836 |
release of cytochrome c from mitochondria |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000266 |
mitochondrial fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O00429 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2000302 |
positive regulation of synaptic vesicle exocytosis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1990910 |
response to hypobaric hypoxia |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1905395 |
response to flavonoid |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904579 |
cellular response to thapsigargin |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1900244 |
positive regulation of synaptic vesicle endocytosis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0099503 |
secretory vesicle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0098835 |
presynaptic endocytic zone membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090650 |
cellular response to oxygen-glucose deprivation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090141 |
positive regulation of mitochondrial fission |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071396 |
cellular response to lipid |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070584 |
mitochondrion morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061003 |
positive regulation of dendritic spine morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0051433 |
BH2 domain binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051260 |
protein homooligomerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048488 |
synaptic vesicle endocytosis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048312 |
intracellular distribution of mitochondria |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043653 |
mitochondrial fragmentation involved in apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0036466 |
synaptic vesicle recycling via endosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0031966 |
mitochondrial membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0030672 |
synaptic vesicle membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0030276 |
clathrin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010637 |
negative regulation of mitochondrial fusion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005905 |
clathrin-coated pit |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005777 |
peroxisome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0000139 |
Golgi membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35303 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000266 |
mitochondrial fission |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003924 |
GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005525 |
GTP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000375 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0016559 |
peroxisome fission |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0015630 |
microtubule cytoskeleton |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0051325) |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0012501 |
programmed cell death |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005905 |
clathrin-coated pit |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005777 |
peroxisome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006897 |
endocytosis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048511 |
rhythmic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008289 |
lipid binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0045202 |
synapse |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005525 |
GTP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0030672 |
synaptic vesicle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0012505 |
endomembrane system |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yang, X et al. (2017) Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice. Redox Biol 12 264-273 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Ashrafian, H et al. (2010) A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. PLoS Genet. 6 e1001000 PubMed GONUTS page
- ↑ Revenu, C et al. (2012) A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Mol. Biol. Cell 23 324-36 PubMed GONUTS page
- ↑ Wang, Z et al. (2012) The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148 228-43 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Losón, OC et al. (2013) Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol. Biol. Cell 24 659-67 PubMed GONUTS page
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 Upadhyay, M et al. (2017) Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Neurobiol. Dis. 100 39-51 PubMed GONUTS page
- ↑ 8.0 8.1 Richter, V et al. (2014) Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission. J. Cell Biol. 204 477-86 PubMed GONUTS page
- ↑ Otera, H et al. (2010) Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J. Cell Biol. 191 1141-58 PubMed GONUTS page
- ↑ Maryanovich, M et al. (2015) An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate. Nat Commun 6 7901 PubMed GONUTS page
- ↑ Whelan, RS et al. (2012) Bax regulates primary necrosis through mitochondrial dynamics. Proc. Natl. Acad. Sci. U.S.A. 109 6566-71 PubMed GONUTS page
- ↑ Ehses, S et al. (2009) Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. J. Cell Biol. 187 1023-36 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Strack, S et al. (2013) Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules. J. Cell Biol. 201 1037-51 PubMed GONUTS page
c
- GO:0006816 ! calcium ion transport
- GO:0071396 ! cellular response to lipid
- GO:0090650 ! cellular response to oxygen-glucose deprivation
- GO:0030054 ! cell junction
- Chordata
- GO:0005905 ! clathrin-coated pit
- GO:0030276 ! clathrin binding
- Craniata
- GO:0005737 ! cytoplasm
- GO:0031410 ! cytoplasmic vesicle
- GO:0005829 ! cytosol
e
g
i
m
- Mammalia
- GO:0016020 ! membrane
- GO:0061025 ! membrane fusion
- Metazoa
- GO:0005874 ! microtubule
- GO:0015630 ! microtubule cytoskeleton
- GO:0008017 ! microtubule binding
- GO:0043653 ! mitochondrial fragmentation involved in apoptotic process
- GO:0005741 ! mitochondrial outer membrane
- GO:0090149 ! mitochondrial membrane fission
- GO:0000266 ! mitochondrial fission
- GO:0031966 ! mitochondrial membrane
- GO:0051882 ! mitochondrial depolarization
- GO:0005739 ! mitochondrion
- GO:0007005 ! mitochondrion organization
- GO:0099073 ! mitochondrion-derived vesicle
- Muridae
- Murinae
- Muroidea
- Mus
- Mus musculus
n
o
p
- GO:0048471 ! perinuclear region of cytoplasm
- GO:0005777 ! peroxisome
- GO:0016559 ! peroxisome fission
- GO:0061003 ! positive regulation of dendritic spine morphogenesis
- GO:0043065 ! positive regulation of apoptotic process
- GO:0090200 ! positive regulation of release of cytochrome c from mitochondria
- GO:0090141 ! positive regulation of mitochondrial fission
- GO:0050714 ! positive regulation of protein secretion
- GO:1900244 ! positive regulation of synaptic vesicle endocytosis
- GO:2000302 ! positive regulation of synaptic vesicle exocytosis
- GO:2001244 ! positive regulation of intrinsic apoptotic signaling pathway
- GO:0098835 ! presynaptic endocytic zone membrane
- GO:0012501 ! programmed cell death
- GO:0044877 ! protein-containing complex binding
- GO:0032991 ! protein-containing complex
- GO:0051259 ! protein complex oligomerization
- GO:0051289 ! protein homotetramerization
- GO:0042803 ! protein homodimerization activity
- GO:0051260 ! protein homooligomerization
- GO:0070585 ! protein localization to mitochondrion
r
- GO:0017137 ! Rab GTPase binding
- GO:1903578 ! regulation of ATP metabolic process
- GO:0010821 ! regulation of mitochondrion organization
- GO:1903146 ! regulation of autophagy of mitochondrion
- GO:1900063 ! regulation of peroxisome organization
- GO:0032459 ! regulation of protein oligomerization
- GO:1904666 ! regulation of ubiquitin protein ligase activity
- GO:0010468 ! regulation of gene expression
- GO:0001836 ! release of cytochrome c from mitochondria
- GO:1905395 ! response to flavonoid
- GO:1990910 ! response to hypobaric hypoxia
- GO:0048511 ! rhythmic process
- Rodentia
s