GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:COBL

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Cobl (synonyms: Kiaa0633)
Protein Name(s) Protein cordon-bleu
External Links
UniProt Q5NBX1
EMBL AY308745
AK122334
AK028833
AK049730
AL669822
AL713914
AL669822
AL713914
AL713914
AL669822
AL713914
AL669822
BC023264
BC060061
U26967
CCDS CCDS36113.1
RefSeq NP_766084.3
XP_006514548.1
UniGene Mm.22847
PDB 3TU5
4JHD
PDBsum 3TU5
4JHD
ProteinModelPortal Q5NBX1
SMR Q5NBX1
IntAct Q5NBX1
MINT MINT-8244298
PhosphoSite Q5NBX1
MaxQB Q5NBX1
PaxDb Q5NBX1
PRIDE Q5NBX1
Ensembl ENSMUST00000046755
ENSMUST00000109650
ENSMUST00000172919
GeneID 12808
KEGG mmu:12808
UCSC uc007ibd.2
uc007ibf.2
uc011xrq.1
CTD 23242
MGI MGI:105056
eggNOG NOG76967
GeneTree ENSGT00530000063608
HOVERGEN HBG081301
InParanoid Q5NBX1
KO K18623
OMA SVGQSCG
OrthoDB EOG7GTT3R
PhylomeDB Q5NBX1
TreeFam TF333490
NextBio 282252
PRO PR:Q5NBX1
Proteomes UP000000589
Bgee Q5NBX1
CleanEx MM_COBL
ExpressionAtlas Q5NBX1
Genevestigator Q5NBX1
GO GO:0030424
GO:0044295
GO:0005938
GO:0005856
GO:0030425
GO:0044294
GO:0043025
GO:0048471
GO:0005886
GO:0001726
GO:0003785
GO:0051764
GO:0051639
GO:0030041
GO:0048669
GO:0048565
GO:0000578
GO:0033504
GO:0001889
GO:0001843
GO:0030903
GO:1900006
GO:1900029
GO:0001757
InterPro IPR019025
IPR003124
Pfam PF09469
PF02205
SMART SM00246
PROSITE PS51082

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1900006

positive regulation of dendrite development

PMID:21725280[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051764

actin crosslink formation

PMID:17956734[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051639

actin filament network formation

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048669

collateral sprouting in absence of injury

PMID:17956734[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048565

digestive tract development

PMID:7586755[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:21725280[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0044295

axonal growth cone

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0044294

dendritic growth cone

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0033504

floor plate development

PMID:7586755[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030903

notochord development

PMID:7586755[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030041

actin filament polymerization

PMID:17956734[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:21725280[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

PMID:21725280[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0005884

actin filament

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003785

actin monomer binding

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0001889

liver development

PMID:7586755[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001757

somite specification

PMID:7586755[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0001726

ruffle

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000578

embryonic axis specification

PMID:7586755[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1900029

positive regulation of ruffle assembly

PMID:17956734[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1312002

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1312002

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001843

neural tube closure

PMID:14512015[4]

ECO:0000316

genetic interaction evidence used in manual assertion

MGI:MGI:2135272

P

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003124

F

Seeded From UniProt

complete

enables

GO:0003785

actin monomer binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039895

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

part_of

GO:0001726

ruffle

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0300

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Schwintzer, L et al. (2011) The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J. 30 3147-59 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 Ahuja, R et al. (2007) Cordon-bleu is an actin nucleation factor and controls neuronal morphology. Cell 131 337-50 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Gasca, S et al. (1995) Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo. Dev. Genet. 17 141-54 PubMed GONUTS page
  4. Carroll, EA et al. (2003) Cordon-bleu is a conserved gene involved in neural tube formation. Dev. Biol. 262 16-31 PubMed GONUTS page