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MOUSE:CD47
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Cd47 | |
| Protein Name(s) | Leukocyte surface antigen CD47
Integrin-associated protein IAP | |
| External Links | ||
| UniProt | Q61735 | |
| EMBL | Z25524 AB012693 BC009094 BC012667 | |
| CCDS | CCDS28212.1 | |
| PIR | S36646 | |
| RefSeq | NP_034711.1 XP_006521874.1 | |
| UniGene | Mm.31752 Mm.390865 | |
| ProteinModelPortal | Q61735 | |
| SMR | Q61735 | |
| BioGrid | 200835 | |
| IntAct | Q61735 | |
| MINT | MINT-1711744 | |
| STRING | 10090.ENSMUSP00000099853 | |
| PhosphoSite | Q61735 | |
| MaxQB | Q61735 | |
| PaxDb | Q61735 | |
| PRIDE | Q61735 | |
| Ensembl | ENSMUST00000084838 | |
| GeneID | 16423 | |
| KEGG | mmu:16423 | |
| UCSC | uc007zkg.1 uc007zkh.1 | |
| CTD | 961 | |
| MGI | MGI:96617 | |
| eggNOG | NOG42016 | |
| GeneTree | ENSGT00390000007697 | |
| HOGENOM | HOG000013020 | |
| HOVERGEN | HBG003808 | |
| InParanoid | Q61735 | |
| KO | K06266 | |
| OMA | VYMKFVA | |
| OrthoDB | EOG79GT78 | |
| PhylomeDB | Q61735 | |
| TreeFam | TF336026 | |
| Reactome | REACT_215628 REACT_216309 REACT_225233 | |
| ChiTaRS | Cd47 | |
| NextBio | 289633 | |
| PRO | PR:Q61735 | |
| Proteomes | UP000000589 | |
| Bgee | Q61735 | |
| ExpressionAtlas | Q61735 | |
| Genevestigator | Q61735 | |
| GO | GO:0070062 GO:0005887 GO:0005886 GO:0070053 GO:0007155 GO:0008228 GO:0008284 GO:0022409 GO:0050729 GO:0050766 GO:0050870 GO:0009617 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR006704 IPR013147 IPR013270 IPR007110 IPR013783 | |
| PANTHER | PTHR10613 | |
| Pfam | PF04549 PF08204 | |
| PROSITE | PS50835 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0045428 |
regulation of nitric oxide biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96617 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070053 |
thrombospondin receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000064788 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050766 |
positive regulation of phagocytosis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96617 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050729 |
positive regulation of inflammatory response |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96617 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0022409 |
positive regulation of cell-cell adhesion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000064788 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96617 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1905450 |
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0098632 |
cell-cell adhesion mediator activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0086080 |
protein binding involved in heterotypic cell-cell adhesion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0071349 |
cellular response to interleukin-12 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0071347 |
cellular response to interleukin-1 |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0071346 |
cellular response to interferon-gamma |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000558) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070053 |
thrombospondin receptor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0051496 |
positive regulation of stress fiber assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0050870 |
positive regulation of T cell activation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0050766 |
positive regulation of phagocytosis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0050766 |
positive regulation of phagocytosis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0050729 |
positive regulation of inflammatory response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1861955 |
P |
regulates_o_has_participant:(EMAPA:36501) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0035696 |
monocyte extravasation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0032680 |
regulation of tumor necrosis factor production |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0032675 |
regulation of interleukin-6 production |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0032655 |
regulation of interleukin-12 production |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0032653 |
regulation of interleukin-10 production |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0032649 |
regulation of interferon-gamma production |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0022409 |
positive regulation of cell-cell adhesion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0016477 |
cell migration |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2308 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0009617 |
response to bacterium |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1861955 |
P |
has_participant:(EMAPA:36501) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0008228 |
opsonization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034113 |
heterotypic cell-cell adhesion |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0086080 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098609 |
cell-cell adhesion |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0098632 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098609 |
cell-cell adhesion |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0098632 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0098632 |
cell-cell adhesion mediator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071349 |
cellular response to interleukin-12 |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070053 |
thrombospondin receptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050870 |
positive regulation of T cell activation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032680 |
regulation of tumor necrosis factor production |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032675 |
regulation of interleukin-6 production |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032655 |
regulation of interleukin-12 production |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032653 |
regulation of interleukin-10 production |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032649 |
regulation of interferon-gamma production |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0022409 |
positive regulation of cell-cell adhesion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q08722 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-MMU-548973 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007155 |
cell adhesion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Alblas, J et al. (2005) Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways. Mol. Cell. Biol. 25 7181-92 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Blanc, L et al. (2009) The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume. Blood 114 3928-34 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Tada, K et al. (2003) Tethering of apoptotic cells to phagocytes through binding of CD47 to Src homology 2 domain-bearing protein tyrosine phosphatase substrate-1. J. Immunol. 171 5718-26 PubMed GONUTS page
- ↑ 5.0 5.1 Verdrengh, M et al. (1999) Integrin-associated protein (IAP)-deficient mice are less susceptible to developing Staphylococcus aureus-induced arthritis. Microbes Infect. 1 745-51 PubMed GONUTS page
c
- GO:0098609 ! cell-cell adhesion
- GO:0098632 ! cell-cell adhesion mediator activity
- GO:0071349 ! cellular response to interleukin-12
- GO:0071222 ! cellular response to lipopolysaccharide
- GO:0071346 ! cellular response to type II interferon
- GO:0071347 ! cellular response to interleukin-1
- GO:0007155 ! cell adhesion
- GO:0016477 ! cell migration
- GO:0009986 ! cell surface
- Chordata
- Craniata
g
m
p
- GO:0005886 ! plasma membrane
- GO:0008284 ! positive regulation of cell population proliferation
- GO:0051496 ! positive regulation of stress fiber assembly
- GO:0050870 ! positive regulation of T cell activation
- GO:0050766 ! positive regulation of phagocytosis
- GO:0050729 ! positive regulation of inflammatory response
- GO:0022409 ! positive regulation of cell-cell adhesion
- GO:0086080 ! protein binding involved in heterotypic cell-cell adhesion
r
- GO:0032649 ! regulation of type II interferon production
- GO:0045428 ! regulation of nitric oxide biosynthetic process
- GO:0032680 ! regulation of tumor necrosis factor production
- GO:0032675 ! regulation of interleukin-6 production
- GO:0032655 ! regulation of interleukin-12 production
- GO:0032653 ! regulation of interleukin-10 production
- GO:0009617 ! response to bacterium
- Rodentia
