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MOUSE:CAPON
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Nos1ap (synonyms: Capon, Kiaa0464) | |
| Protein Name(s) | Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
C-terminal PDZ ligand of neuronal nitric oxide synthase protein Nitric oxide synthase 1 adaptor protein | |
| External Links | ||
| UniProt | Q9D3A8 | |
| EMBL | AK018149 AC119431 AC123650 AC125017 AC125021 AK122290 | |
| CCDS | CCDS48438.1 | |
| RefSeq | NP_001103455.1 | |
| UniGene | Mm.487078 | |
| ProteinModelPortal | Q9D3A8 | |
| SMR | Q9D3A8 | |
| PhosphoSite | Q9D3A8 | |
| MaxQB | Q9D3A8 | |
| PRIDE | Q9D3A8 | |
| DNASU | 70729 | |
| Ensembl | ENSMUST00000160456 | |
| GeneID | 70729 | |
| KEGG | mmu:70729 | |
| UCSC | uc011wvt.1 | |
| CTD | 9722 | |
| MGI | MGI:1917979 | |
| eggNOG | NOG244289 | |
| GeneTree | ENSGT00510000046975 | |
| HOGENOM | HOG000111298 | |
| HOVERGEN | HBG050788 | |
| InParanoid | Q9D3A8 | |
| KO | K16513 | |
| OMA | QNTMGSQ | |
| OrthoDB | EOG7JDQXM | |
| TreeFam | TF317226 | |
| NextBio | 332169 | |
| PRO | PR:Q9D3A8 | |
| Proteomes | UP000000589 | |
| Bgee | Q9D3A8 | |
| ExpressionAtlas | Q9D3A8 | |
| Genevestigator | Q9D3A8 | |
| Gene3D | 2.30.29.30 | |
| InterPro | IPR011993 IPR006020 | |
| Pfam | PF00640 | |
| SMART | SM00462 | |
| PROSITE | PS01179 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
Contributes to |
GO:0004517 |
nitric-oxide synthase activity |
ECO:0000314 |
F |
Syntesis of nitrous oxide; insufficient amounts lead to inhibition of brain activity as well as increased ADHD |
complete | ||||
|
part_of |
GO:0030018 |
Z disc |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
colocalizes_with |
GO:0005901 |
caveola |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0033017 |
sarcoplasmic reticulum membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0000948) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050998 |
nitric-oxide synthase binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
part_of:(UBERON:0000948) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0000948) |
Seeded From UniProt |
complete | ||
|
colocalizes_with |
GO:0030315 |
T-tubule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000746) |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:2000170 |
positive regulation of peptidyl-cysteine S-nitrosylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
P |
Seeded From UniProt |
complete | ||
|
colocalizes_with |
GO:1990454 |
L-type voltage-gated calcium channel complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
colocalizes_with |
GO:1902937 |
inward rectifier potassium channel complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1901841 |
regulation of high voltage-gated calcium channel activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1901215 |
negative regulation of neuron death |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098794 |
postsynapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098793 |
presynapse |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050998 |
nitric-oxide synthase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
F |
Seeded From UniProt |
complete | ||
|
colocalizes_with |
GO:0031965 |
nuclear membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030165 |
PDZ domain binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0008150 |
biological_process |
ECO:0000307 |
no biological data found used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0002020 |
protease binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620106 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O75052 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098974 |
postsynaptic actin cytoskeleton organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O75052 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060307 |
regulation of ventricular cardiac muscle cell membrane repolarization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O75052 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0003062 |
regulation of heart rate by chemical signal |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O75052 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gao, Y & Heldt, SA (2015) Lack of neuronal nitric oxide synthase results in attention deficit hyperactivity disorder-like behaviors in mice. Behav. Neurosci. 129 50-61 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Beigi, F et al. () Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, CAPON. Nitric Oxide 21 226-33 PubMed GONUTS page
- ↑ Treuer, AV & Gonzalez, DR (2014) NOS1AP modulates intracellular Ca(2+) in cardiac myocytes and is up-regulated in dystrophic cardiomyopathy. Int J Physiol Pathophysiol Pharmacol 6 37-46 PubMed GONUTS page
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