MOUSE:AURKB

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Aurkb (synonyms: Aik2, Aim1, Airk2, Ark2, Stk1, Stk12, Stk5)
Protein Name(s)	Aurora kinase B Aurora 1 Aurora- and IPL1-like midbody-associated protein 1 Aurora/IPL1-related kinase 2 ARK-2 Aurora-related kinase 2 STK-1 Serine/threonine-protein kinase 12 Serine/threonine-protein kinase 5 Serine/threonine-protein kinase aurora-B
External Links
UniProt	O70126
EMBL	D21099 U69107 AK075951 AK132006 AL645902 CH466601 BC003261
CCDS	CCDS24877.1
PIR	JC4665
RefSeq	NP_035626.1
UniGene	Mm.3488
ProteinModelPortal	O70126
SMR	O70126
BioGrid	203547
IntAct	O70126
MINT	MINT-1341009
BindingDB	O70126
ChEMBL	CHEMBL1075275
PhosphoSite	O70126
MaxQB	O70126
PaxDb	O70126
PRIDE	O70126
Ensembl	ENSMUST00000021277 ENSMUST00000108666
GeneID	20877
KEGG	mmu:20877
UCSC	uc007jpa.1
CTD	9212
MGI	MGI:107168
eggNOG	COG0515
GeneTree	ENSGT00770000120530
HOGENOM	HOG000233016
HOVERGEN	HBG108519
InParanoid	O70126
KO	K11479
OMA	HPWVRAN
OrthoDB	EOG74FF1F
TreeFam	TF351439
Reactome	REACT_198961 REACT_207679 REACT_226135 REACT_256756
ChiTaRS	Aurkb
NextBio	299727
PRO	PR:O70126
Proteomes	UP000000589
Bgee	O70126
CleanEx	MM_AURKB
Genevestigator	O70126
GO	GO:0010369 GO:0032133 GO:0000780 GO:0005737 GO:0045171 GO:0000776 GO:0030496 GO:0097431 GO:0005634 GO:0005524 GO:0035174 GO:0046872 GO:0004674 GO:0009838 GO:0007568 GO:0008283 GO:0034644 GO:0036089 GO:0031565 GO:0043988 GO:0051256 GO:0002903 GO:0032466 GO:0032091 GO:0000122 GO:0032467 GO:0034501 GO:0006468 GO:0031577 GO:0043146
InterPro	IPR028772 IPR011009 IPR000719 IPR017441 IPR002290 IPR008271
PANTHER	PTHR24350:SF4
Pfam	PF00069
SMART	SM00220
SUPFAM	SSF56112
PROSITE	PS00107 PS50011 PS00108

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006468	protein phosphorylation	PMID:12458200^[1]	ECO:0000314			P		Fig. 2A shows Aurora-B phosphorylating Vimentin	complete
involved_in	GO:0051256	mitotic spindle midzone assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
involved_in	GO:0043988	histone H3-S28 phosphorylation	PMID:24034696^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0036089	cleavage furrow formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
enables	GO:0035174	histone serine kinase activity	PMID:24034696^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0034644	cellular response to UV	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
involved_in	GO:0034501	protein localization to kinetochore	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
involved_in	GO:0032467	positive regulation of cytokinesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
involved_in	GO:0032466	negative regulation of cytokinesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7YRC6	P		Seeded From UniProt	complete
involved_in	GO:0044878	mitotic cytokinesis checkpoint	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7YRC6	P		Seeded From UniProt	complete
involved_in	GO:0009838	abscission	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7YRC6	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q7YRC6	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	PMID:24034696^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0002903	negative regulation of B cell apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
part_of	GO:0051233	spindle midzone	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0024227 PANTHER:PTN000681967 SGD:S000006130 UniProtKB:Q9UQB9 WB:WBGene00000099 dictyBase:DDB_G0279343	C		Seeded From UniProt	complete
enables	GO:0035174	histone serine kinase activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107168 MGI:MGI:894678 PANTHER:PTN000681967	F		Seeded From UniProt	complete
involved_in	GO:0032465	regulation of cytokinesis	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000681967 SGD:S000006130	P		Seeded From UniProt	complete
part_of	GO:0032133	chromosome passenger complex	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0024227 MGI:MGI:107168 PANTHER:PTN000681967 PomBase:SPCC320.13c SGD:S000006130 UniProtKB:Q96GD4 dictyBase:DDB_G0279343	C		Seeded From UniProt	complete
part_of	GO:0031616	spindle pole centrosome	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000681967 UniProtKB:O14965 WB:WBGene00000098	C		Seeded From UniProt	complete
involved_in	GO:0007052	mitotic spindle organization	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:894678 PANTHER:PTN000681967	P		Seeded From UniProt	complete
part_of	GO:0005876	spindle microtubule	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000681967 SGD:S000006130 UniProtKB:O14965	C		Seeded From UniProt	complete
part_of	GO:0000780	condensed nuclear chromosome, centromeric region	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0024227 MGI:MGI:107168 PANTHER:PTN000681967 UniProtKB:Q96GD4	C		Seeded From UniProt	complete
part_of	GO:1990023	mitotic spindle midzone	PMID:14751927^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904355	positive regulation of telomere capping	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051973	positive regulation of telomerase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051256	mitotic spindle midzone assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0036089	cleavage furrow formation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0036089	cleavage furrow formation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621625	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034644	cellular response to UV	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034501	protein localization to kinetochore	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032467	positive regulation of cytokinesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032212	positive regulation of telomere maintenance via telomerase	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
part_of	GO:0032133	chromosome passenger complex	PMID:20562830^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0032133	chromosome passenger complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032091	negative regulation of protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
part_of	GO:0030496	midbody	PMID:9514916^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621625	C		Seeded From UniProt	complete
enables	GO:0019900	kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	F		Seeded From UniProt	complete
part_of	GO:0010369	chromocenter	PMID:19283064^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000017)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007051	spindle organization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006468	protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
part_of	GO:0005819	spindle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621625	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:14751927^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	F		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621625	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002903	negative regulation of B cell apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
part_of	GO:0000780	condensed nuclear chromosome, centromeric region	PMID:14751927^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0000780	condensed nuclear chromosome, centromeric region	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
part_of	GO:0000779	condensed chromosome, centromeric region	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
part_of	GO:0000776	kinetochore	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q96GD4	P		Seeded From UniProt	complete
involved_in	GO:0036089	cleavage furrow formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O55099 ensembl:ENSRNOP00000072371	P		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O55099 ensembl:ENSRNOP00000072371	C		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O55099 ensembl:ENSRNOP00000072371	P		Seeded From UniProt	complete
involved_in	GO:0007568	aging	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O55099 ensembl:ENSRNOP00000072371	P		Seeded From UniProt	complete
part_of	GO:0005819	spindle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O55099 ensembl:ENSRNOP00000072371	C		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O55099 ensembl:ENSRNOP00000072371	F		Seeded From UniProt	complete
involved_in	GO:1904355	positive regulation of telomere capping	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0051973	positive regulation of telomerase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0051256	mitotic spindle midzone assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0036089	cleavage furrow formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0034644	cellular response to UV	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0034501	protein localization to kinetochore	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0032467	positive regulation of cytokinesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0032212	positive regulation of telomere maintenance via telomerase	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
part_of	GO:0032133	chromosome passenger complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
involved_in	GO:0032091	negative regulation of protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
enables	GO:0019900	kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	F		Seeded From UniProt	complete
involved_in	GO:0007051	spindle organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	F		Seeded From UniProt	complete
involved_in	GO:0002903	negative regulation of B cell apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
part_of	GO:0000780	condensed nuclear chromosome, centromeric region	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
part_of	GO:0000779	condensed chromosome, centromeric region	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
part_of	GO:0000776	kinetochore	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q96GD4 ensembl:ENSP00000313950	P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271 InterPro:IPR030616	F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028772	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	P		Seeded From UniProt	complete
involved_in	GO:0007094	mitotic spindle assembly checkpoint	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028772	P		Seeded From UniProt	complete
part_of	GO:0032133	chromosome passenger complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028772	C		Seeded From UniProt	complete
involved_in	GO:0032467	positive regulation of cytokinesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028772	P		Seeded From UniProt	complete
involved_in	GO:0043988	histone H3-S28 phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028772	P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-MMU-9023138	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	Reactome:R-MMU-9023138	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206	C		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0723	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
part_of	GO:0000775	chromosome, centromeric region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0137 UniProtKB-SubCell:SL-0047	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0158 UniProtKB-SubCell:SL-0468	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
part_of	GO:0005819	spindle	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0251	C		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0469	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Goto, H et al. (2003) Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J. Biol. Chem. 278 8526-30 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Frangini, A et al. (2013) The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes. Mol. Cell 51 647-61 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Zhang, Y et al. (2004) Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression. Blood 103 3717-26 PubMed GONUTS page
↑ Orpinell, M et al. (2010) The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates. EMBO J. 29 2381-94 PubMed GONUTS page
↑ Shindo, M et al. (1998) cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem. Biophys. Res. Commun. 244 285-92 PubMed GONUTS page
↑ Parra, MT et al. (2009) Sequential assembly of centromeric proteins in male mouse meiosis. PLoS Genet. 5 e1000417 PubMed GONUTS page

[PMID:12458200-1] Goto, H et al. (2003) Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J. Biol. Chem. 278 8526-30 PubMed GONUTS page

[PMID:24034696-2] 2.0 ^2.1 ^2.2 Frangini, A et al. (2013) The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes. Mol. Cell 51 647-61 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:14751927-4] 4.0 ^4.1 ^4.2 Zhang, Y et al. (2004) Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression. Blood 103 3717-26 PubMed GONUTS page

[PMID:20562830-5] Orpinell, M et al. (2010) The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates. EMBO J. 29 2381-94 PubMed GONUTS page

[PMID:9514916-6] Shindo, M et al. (1998) cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2. Biochem. Biophys. Res. Commun. 244 285-92 PubMed GONUTS page

[PMID:19283064-7] Parra, MT et al. (2009) Sequential assembly of centromeric proteins in male mouse meiosis. PLoS Genet. 5 e1000417 PubMed GONUTS page

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