MIMIV:SYY

Species (Taxon ID)	Acanthamoeba polyphaga mimivirus (APMV). (212035)
Gene Name(s)	YARS
Protein Name(s)	Tyrosine--tRNA ligase Tyrosyl-tRNA synthetase TyrRS
External Links
UniProt	Q5UPJ7
EMBL	AY653733
RefSeq	YP_003986615.1
PDB	2J5B
PDBsum	2J5B
SMR	Q5UPJ7
MINT	Q5UPJ7
DrugBank	DB03978
GeneID	9924723
KEGG	vg:9924723
KO	K01866
OrthoDB	5889at10239
BRENDA	6.1.1.1
SABIO-RK	Q5UPJ7
EvolutionaryTrace	Q5UPJ7
Proteomes	UP000001134
GO	GO:0005524 GO:0042802 GO:0042803 GO:0072545 GO:0004831 GO:0006437
DisProt	DP00726
Gene3D	3.40.50.620
InterPro	IPR002305 IPR014729 IPR023617
Pfam	PF00579
PIRSF	PIRSF006588

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0042803	protein homodimerization activity	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
enables	GO:0005524	ATP binding	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
involved_in	GO:0006437	tyrosyl-tRNA aminoacylation	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt
enables	GO:0004831	tyrosine-tRNA ligase activity	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
enables	GO:0072545	tyrosine binding	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
enables	GO:0042802	identical protein binding	PMID:23384724^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q5UPJ7	F	Seeded From UniProt
enables	GO:0000166	nucleotide binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	F	Seeded From UniProt
enables	GO:0004812	aminoacyl-tRNA ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	F	Seeded From UniProt
enables	GO:0004831	tyrosine-tRNA ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023617	F	Seeded From UniProt
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	F	Seeded From UniProt
involved_in	GO:0006418	tRNA aminoacylation for protein translation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	P	Seeded From UniProt
enables	GO:0004831	tyrosine-tRNA ligase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:6.1.1.1	F	Seeded From UniProt
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt
enables	GO:0004812	aminoacyl-tRNA ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0030	F	Seeded From UniProt
enables	GO:0016874	ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0436	F	Seeded From UniProt
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt
involved_in	GO:0006412	translation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0648	P	Seeded From UniProt
enables	GO:0042803	protein homodimerization activity	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
enables	GO:0005524	ATP binding	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
involved_in	GO:0006437	tyrosyl-tRNA aminoacylation	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt
enables	GO:0004831	tyrosine-tRNA ligase activity	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
enables	GO:0072545	tyrosine binding	PMID:17855524^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt
enables	GO:0042802	identical protein binding	PMID:23384724^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q5UPJ7	F	Seeded From UniProt
enables	GO:0000166	nucleotide binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	F	Seeded From UniProt
enables	GO:0004812	aminoacyl-tRNA ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	F	Seeded From UniProt
enables	GO:0004831	tyrosine-tRNA ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023617	F	Seeded From UniProt
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	F	Seeded From UniProt
involved_in	GO:0006418	tRNA aminoacylation for protein translation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002305	P	Seeded From UniProt
enables	GO:0004831	tyrosine-tRNA ligase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:6.1.1.1	F	Seeded From UniProt
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt
enables	GO:0004812	aminoacyl-tRNA ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0030	F	Seeded From UniProt
enables	GO:0016874	ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0436	F	Seeded From UniProt
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt
	GO:0004831	tyrosine-tRNA ligase activity	PMID:17855524^[1]	ECO:0005801	enzymatic activity assay evidence used in manual assertion		F	Fig1. A shows that Tyrosine--tRNA ligase (TyrRS) in Acanthamoeba polyphaga mimivirus (APMV) an amino acid activation activity in the presence of tyrosine.	complete CACAO 13835
involved_in	GO:0006412	translation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0648	P	Seeded From UniProt
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 Abergel, C et al. (2007) Virus-encoded aminoacyl-tRNA synthetases: structural and functional characterization of mimivirus TyrRS and MetRS. J. Virol. 81 12406-17 PubMed GONUTS page
↑ ^2.0 ^2.1 Choudhury, A & Banerjee, R (2013) The N-terminal fragment of Acanthamoeba polyphaga mimivirus tyrosyl-tRNA synthetase (TyrRS(apm)) is a monomer in solution. FEBS Lett. 587 590-9 PubMed GONUTS page

[PMID:17855524-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 Abergel, C et al. (2007) Virus-encoded aminoacyl-tRNA synthetases: structural and functional characterization of mimivirus TyrRS and MetRS. J. Virol. 81 12406-17 PubMed GONUTS page

[PMID:23384724-2] 2.0 ^2.1 Choudhury, A & Banerjee, R (2013) The N-terminal fragment of Acanthamoeba polyphaga mimivirus tyrosyl-tRNA synthetase (TyrRS(apm)) is a monomer in solution. FEBS Lett. 587 590-9 PubMed GONUTS page

[1]

[2]

MIMIV:SYY

Contents

Annotations

Notes

References

a

i

l

m

n

p

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools