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LEIMA:Q7K9G0

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Species (Taxon ID) Leishmania major. (5664)
Gene Name(s) MST (ECO:0000313 with EMBL:CAC85741.1)
Protein Name(s) 3-mercaptopyruvate sulfurtransferase (ECO:0000313 with EMBL:CAJ02017.1)

Mercaptopyruvate sulfurtransferase (ECO:0000313 with EMBL:CAC85741.1)

External Links
UniProt Q7K9G0
EMBL AJ313201
FR796401
RefSeq XP_001687574.1
PDB 1OKG
PDBsum 1OKG
SMR Q7K9G0
EnsemblProtists LmjF.05.0970:mRNA
GeneID 5648962
KEGG lma:LMJF_05_0970
HOGENOM HOG000255200
KO K01011
OMA NYCGRLW
BRENDA 2.8.1.2
EvolutionaryTrace Q7K9G0
Proteomes UP000000542
GO GO:0005829
GO:0016784
GO:0019499
GO:0019343
Gene3D 3.30.1670.10
3.40.250.10
InterPro IPR015206
IPR001763
Pfam PF09122
PF00581
SMART SM00450
SUPFAM SSF52821
PROSITE PS50206

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016784

3-mercaptopyruvate sulfurtransferase activity

PMID:12419809[1]

ECO:0000314

F

Figure 3B - Western blot analysis of the expression of 3-mercaptopyruvate sulfurtransferase (MST) when L. major cells were exposed to hypo-sulfur stress. Lane 1 contains the control while lane 2 contains cells exposed hypo-sulfur stress. Exposed L. major cells responded to hypo-sulfur stress over 24 h by increased expression of MST.

complete
CACAO 4793

involved_in

GO:0019499

cyanide metabolic process

PMID:12419809[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0019343

cysteine biosynthetic process via cystathionine

PMID:12419809[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016784

3-mercaptopyruvate sulfurtransferase activity

PMID:12419809[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:12419809[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016784

3-mercaptopyruvate sulfurtransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.8.1.2

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Williams, RA et al. (2003) 3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism. J. Biol. Chem. 278 1480-6 PubMed GONUTS page