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LEIMA:Q5C8V6

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Species (Taxon ID) Leishmania major. (5664)
Gene Name(s) POT1 (ECO:0000313 with EMBL:AAW52506.1) (synonyms: AAT21 (ECO:0000313 with EMBL:CAJ02735.1))
Protein Name(s) Polyamine transporter (ECO:0000313 with EMBL:AAW52506.1)

Putative amino acid permease (ECO:0000313 with EMBL:CAJ02735.1)

External Links
UniProt Q5C8V6
EMBL AY727900
FR796410
RefSeq XP_001687631.1
ProteinModelPortal Q5C8V6
TCDB 2.A.3.12.1
EnsemblProtists LmjF.14.0320:mRNA
GeneID 5650231
KEGG lma:LMJF_14_0320
HOGENOM HOG000256163
InParanoid Q5C8V6
KO K16262
OMA MCILATI
Proteomes UP000000542
GO GO:0016021
GO:0015171
InterPro IPR002293
PANTHER PTHR11785
Pfam PF13520

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003333

amino acid transmembrane transport

PMID:15632173[1]

ECO:0000315

P

Figure 3B - The gene encoding for LmPOT1 was cloned in the pHD309 vector enabling the integration of LmPOT1 into T. brucei, an organism related to L. major which has a low putrescine uptake. A control was made by inserting the empty vector into T. brucei. Putrescine transport was measured in both strains. The LmPOT1 T. brucei strain showed a significant ability to uptake putrescine while the control's putrescine uptake was negligible.

complete
CACAO 4822

involved_in

GO:1903710

spermine transmembrane transport

PMID:15632173[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015847

putrescine transport

PMID:15632173[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015606

spermidine transmembrane transporter activity

PMID:15632173[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015489

putrescine transmembrane transporter activity

PMID:15632173[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15632173[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1903711

spermidine transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015606

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002293

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002293

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002293

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Hasne, MP & Ullman, B (2005) Identification and characterization of a polyamine permease from the protozoan parasite Leishmania major. J. Biol. Chem. 280 15188-94 PubMed GONUTS page