LEIMA:Q5C8V6

Species (Taxon ID)	Leishmania major. (5664)
Gene Name(s)	POT1 (ECO:0000313 with EMBL:AAW52506.1) (synonyms: AAT21 (ECO:0000313 with EMBL:CAJ02735.1))
Protein Name(s)	Polyamine transporter (ECO:0000313 with EMBL:AAW52506.1) Putative amino acid permease (ECO:0000313 with EMBL:CAJ02735.1)
External Links
UniProt	Q5C8V6
EMBL	AY727900 FR796410
RefSeq	XP_001687631.1
ProteinModelPortal	Q5C8V6
TCDB	2.A.3.12.1
EnsemblProtists	LmjF.14.0320:mRNA
GeneID	5650231
KEGG	lma:LMJF_14_0320
HOGENOM	HOG000256163
InParanoid	Q5C8V6
KO	K16262
OMA	MCILATI
Proteomes	UP000000542
GO	GO:0016021 GO:0015171
InterPro	IPR002293
PANTHER	PTHR11785
Pfam	PF13520

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0003333	amino acid transmembrane transport	PMID:15632173	ECO:0000315			P		Figure 3B - The gene encoding for LmPOT1 was cloned in the pHD309 vector enabling the integration of LmPOT1 into T. brucei, an organism related to L. major which has a low putrescine uptake. A control was made by inserting the empty vector into T. brucei. Putrescine transport was measured in both strains. The LmPOT1 T. brucei strain showed a significant ability to uptake putrescine while the control's putrescine uptake was negligible.	complete CACAO 4822
involved_in	GO:1903710	spermine transmembrane transport	PMID:15632173	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0015847	putrescine transport	PMID:15632173	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0015606	spermidine transmembrane transporter activity	PMID:15632173	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015489	putrescine transmembrane transporter activity	PMID:15632173	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:15632173	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1903711	spermidine transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015606	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002293	C		Seeded From UniProt	complete
enables	GO:0022857	transmembrane transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002293	F		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002293	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
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References

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