LEIMA:Q4QBE5

Species (Taxon ID)	Leishmania major. (5664)
Gene Name(s)	No Information Provided.
Protein Name(s)	Uncharacterized protein (ECO:0000313 with EMBL:CAJ04008.1)
External Links
UniProt	Q4QBE5
EMBL	FR796419
RefSeq	XP_001683353.1
ProteinModelPortal	Q4QBE5
EnsemblProtists	LmjF.23.0290:mRNA
GeneID	5651989
KEGG	lma:LMJF_23_0290
HOGENOM	HOG000257416
InParanoid	Q4QBE5
OMA	HSITCEV
Proteomes	UP000000542
GO	GO:0030896 GO:0005634 GO:0000077 GO:0006281
InterPro	IPR007150
PANTHER	PTHR12900
Pfam	PF04005

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0044778	meiotic DNA integrity checkpoint	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0026417 PANTHER:PTN000307391	P	Seeded From UniProt	complete
part_of	GO:0035861	site of double-strand break	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000307391 PomBase:SPAC20G4.04c	C	Seeded From UniProt	complete
involved_in	GO:0033314	mitotic DNA replication checkpoint	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000307391 PomBase:SPAC20G4.04c	P	Seeded From UniProt	complete
involved_in	GO:0031573	intra-S DNA damage checkpoint	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000307391 PomBase:SPAC20G4.04c	P	Seeded From UniProt	complete
part_of	GO:0030896	checkpoint clamp complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0026417 PANTHER:PTN000307391 PomBase:SPAC20G4.04c SGD:S000004279	C	Seeded From UniProt	complete
involved_in	GO:0006289	nucleotide-excision repair	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000307391 WB:WBGene00002042	P	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0026417 MGI:MGI:1277962 PANTHER:PTN000307391	P	Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000307391 PomBase:SPAC20G4.04c SGD:S000004279 WB:WBGene00002042	P	Seeded From UniProt	complete
part_of	GO:0030896	checkpoint clamp complex	PMID:24118609^[2]	ECO:0000353	physical interaction evidence used in manual assertion	GeneDB:LmjF.15.0980	C	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:24118609^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	PMID:21291918^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21291918^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	PMID:24118609^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0000723	telomere maintenance	PMID:24118609^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0000077	DNA damage checkpoint	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007150 InterPro:IPR016580	P	Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016580	C	Seeded From UniProt	complete
part_of	GO:0030896	checkpoint clamp complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007150 InterPro:IPR016580	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
involved_in	GO:0000075	cell cycle checkpoint	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000954759	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Damasceno, JD et al. (2013) LmHus1 is required for the DNA damage response in Leishmania major and forms a complex with an unusual Rad9 homologue. Mol. Microbiol. 90 1074-87 PubMed GONUTS page
↑ ^3.0 ^3.1 Nunes, VS et al. (2011) The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response. Mol. Biochem. Parasitol. 177 65-9 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:24118609-2] 2.0 ^2.1 ^2.2 ^2.3 Damasceno, JD et al. (2013) LmHus1 is required for the DNA damage response in Leishmania major and forms a complex with an unusual Rad9 homologue. Mol. Microbiol. 90 1074-87 PubMed GONUTS page

[PMID:21291918-3] 3.0 ^3.1 Nunes, VS et al. (2011) The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response. Mol. Biochem. Parasitol. 177 65-9 PubMed GONUTS page

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LEIMA:Q4QBE5

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