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LEIMA:IUNH

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Species (Taxon ID) Leishmania major. (5664)
Gene Name(s) NSNH
Protein Name(s) Inosine-uridine preferring nucleoside hydrolase

IU-NH IU-nucleoside hydrolase Non-specific nucleoside hydrolase Purine nucleosidase

External Links
UniProt P83851
EMBL AY533501
PDB 1EZR
PDBsum 1EZR
ProteinModelPortal P83851
SMR P83851
UniPathway UPA00606
EvolutionaryTrace P83851
GO GO:0005509
GO:0047724
GO:0008477
GO:0045437
GO:0009117
GO:0043101
Gene3D 3.90.245.10
InterPro IPR015910
IPR023186
IPR001910
PANTHER PTHR12304
Pfam PF01156
SUPFAM SSF53590
PROSITE PS01247

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0047724

inosine nucleosidase activity

PMID:10409664[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0045437

uridine nucleosidase activity

PMID:10409664[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008477

purine nucleosidase activity

PMID:10409664[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

PMID:10409664[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016799

hydrolase activity, hydrolyzing N-glycosyl compounds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015910

F

Seeded From UniProt

complete

enables

GO:0045437

uridine nucleosidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.2.3

F

Seeded From UniProt

complete

enables

GO:0047724

inosine nucleosidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.2.2

F

Seeded From UniProt

complete

involved_in

GO:0043101

purine-containing compound salvage

PMID:10409664[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009117

nucleotide metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0546

P

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Shi, W et al. (1999) Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure. J. Biol. Chem. 274 21114-20 PubMed GONUTS page