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LAMBD:VLYS

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Species (Taxon ID) Escherichia phage lambda (Bacteriophage lambda). (10710)
Gene Name(s) S
Protein Name(s) Antiholin (ECO:0000303 with PMID:8878031[1])

Lysis inhibitor S-107 (ECO:0000303 with PMID:8878031[1]) Holin (ECO:0000303 with PMID:8878031[1]) Lysis protein S-105 (ECO:0000303 with PMID:8878031[1]) gpS protein

External Links
UniProt P03705
EMBL J02459
M14035
PIR H94164
RefSeq NP_040644.1
YP_001551775.1
IntAct P03705
TCDB 1.E.2.1.1
GeneID 2703479
5740919
KEGG vg:2703479
vg:5740919
OrthoDB VOG090001HJ
Proteomes UP000001711
GO GO:0020002
GO:0016021
GO:0034291
InterPro IPR006481
Pfam PF05106
TIGRFAMs TIGR01594

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0044659

cytolysis by virus of host cell

PMID:9573208[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

PMID:2137120[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

PMID:11029427[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0034291

canonical holin activity

PMID:11361346[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

PMID:6213604[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0044660

cytolysis by virus via pore formation in host cell membrane

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0034291

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1043

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1030
UniProtKB-KW:KW-1032
UniProtKB-SubCell:SL-0373

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0019835

cytolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0204

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Bläsi, U & Young, R (1996) Two beginnings for a single purpose: the dual-start holins in the regulation of phage lysis. Mol. Microbiol. 21 675-82 PubMed GONUTS page
  2. Smith, DL et al. (1998) Purification and biochemical characterization of the lambda holin. J. Bacteriol. 180 2531-40 PubMed GONUTS page
  3. Zagotta, MT & Wilson, DB (1990) Oligomerization of the bacteriophage lambda S protein in the inner membrane of Escherichia coli. J. Bacteriol. 172 912-21 PubMed GONUTS page
  4. Gründling, A et al. (2000) Dimerization between the holin and holin inhibitor of phage lambda. J. Bacteriol. 182 6075-81 PubMed GONUTS page
  5. Ramanculov, E & Young, R (2001) Functional analysis of the phage T4 holin in a lambda context. Mol. Genet. Genomics 265 345-53 PubMed GONUTS page
  6. Wilson, DB (1982) Effect of the lambda S gene product on properties of the Escherichia coli inner membrane. J. Bacteriol. 151 1403-10 PubMed GONUTS page