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I34A1:NEP

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Species (Taxon ID) Influenza A virus (strain A/Puerto Rico/8/1934 H1N1). (211044)
Gene Name(s) NS
Protein Name(s) Nuclear export protein

NEP Non-structural protein 2 NS2

External Links
UniProt P03508
EMBL V01104
J02150
EF467817
AF389122
CY009448
RefSeq NP_040983.1
PDB 1PD3
PDBsum 1PD3
ProteinModelPortal P03508
SMR P03508
IntAct P03508
MINT MINT-6376762
GeneID 956532
Reactome REACT_6145
REACT_6147
REACT_6179
REACT_6198
REACT_6212
REACT_6235
REACT_6321
REACT_6326
REACT_6351
REACT_9491
EvolutionaryTrace P03508
Proteomes UP000009255
GO GO:0005829
GO:0030666
GO:0031904
GO:0005576
GO:0042025
GO:0005654
GO:0019012
GO:0019064
GO:0075733
GO:0019065
GO:0006405
GO:0019061
GO:0046718
GO:0019070
GO:0019072
GO:0019058
GO:0016032
GO:0019076
GO:0019083
GO:0019068
InterPro IPR000968
Pfam PF00601

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0039675

exit of virus from host cell nucleus through nuclear pore

PMID:12921991[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006405

RNA export from nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000968

P

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000968

C

Seeded From UniProt

complete

involved_in

GO:0006405

RNA export from nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568473

P

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568473

C

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568473

C

Seeded From UniProt

complete

involved_in

GO:0039675

exit of virus from host cell nucleus through nuclear pore

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568473

P

Seeded From UniProt

complete

involved_in

GO:0075733

intracellular transport of virus

Reactome:R-HSA-168893
Reactome:R-HSA-168880
Reactome:R-HSA-168857

ECO:0000304

author statement supported by traceable reference used in manual assertion



P

Seeded From UniProt

complete

involved_in

GO:0046761

viral budding from plasma membrane

Reactome:R-HSA-168860

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031904

endosome lumen

Reactome:R-HSA-168324
Reactome:R-HSA-168313
Reactome:R-HSA-168312
Reactome:R-HSA-168306
Reactome:R-HSA-168299
Reactome:R-HSA-168285

ECO:0000304

author statement supported by traceable reference used in manual assertion






C

Seeded From UniProt

complete

part_of

GO:0030666

endocytic vesicle membrane

Reactome:R-HSA-168299

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0019072

viral genome packaging

Reactome:R-HSA-168895
Reactome:R-HSA-168303

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

involved_in

GO:0019065

receptor-mediated endocytosis of virus by host cell

Reactome:R-HSA-168285

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0019064

fusion of virus membrane with host plasma membrane

Reactome:R-HSA-168312
Reactome:R-HSA-168306
Reactome:R-HSA-168288

ECO:0000304

author statement supported by traceable reference used in manual assertion



P

Seeded From UniProt

complete

involved_in

GO:0019062

virion attachment to host cell

Reactome:R-HSA-168272

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0019061

uncoating of virus

Reactome:R-HSA-168313
Reactome:R-HSA-168299

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-195926
Reactome:R-HSA-192841
Reactome:R-HSA-168895
Reactome:R-HSA-168880
Reactome:R-HSA-168860

ECO:0000304

author statement supported by traceable reference used in manual assertion





C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-168893
Reactome:R-HSA-168880
Reactome:R-HSA-168857

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-168870
Reactome:R-HSA-168860
Reactome:R-HSA-168285
Reactome:R-HSA-168272

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1048
UniProtKB-SubCell:SL-0414

C

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946
UniProtKB-SubCell:SL-0274

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Cros, JF & Palese, P (2003) Trafficking of viral genomic RNA into and out of the nucleus: influenza, Thogoto and Borna disease viruses. Virus Res. 95 3-12 PubMed GONUTS page