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HV1H2:GAG
Contents
| Species (Taxon ID) | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)(HIV-1). (11706) | |
| Gene Name(s) | gag | |
| Protein Name(s) | Gag polyprotein
Pr55Gag Matrix protein p17 MA Capsid protein p24 CA Spacer peptide 1 (ECO:0000250 with UniProtKB:P12493) SP1 p2 Nucleocapsid protein p7 NC Spacer peptide 2 (ECO:0000250 with UniProtKB:P12493) SP2 p1 p6-gag | |
| External Links | ||
| UniProt | P04591 | |
| EMBL | K03455 | |
| RefSeq | NP_057850.1 | |
| PDB | 1TSQ 1TSU | |
| PDBsum | 1TSQ 1TSU | |
| ProteinModelPortal | P04591 | |
| SMR | P04591 | |
| BioGrid | 1205537 | |
| IntAct | P04591 | |
| GeneID | 155030 | |
| KEGG | vg:155030 | |
| Reactome | R-HSA-162585 R-HSA-162588 R-HSA-162592 R-HSA-162594 R-HSA-164516 R-HSA-164525 R-HSA-164843 R-HSA-173107 R-HSA-174490 R-HSA-174495 R-HSA-175474 R-HSA-175567 R-HSA-177539 R-HSA-180689 R-HSA-180910 | |
| EvolutionaryTrace | P04591 | |
| Proteomes | UP000002241 | |
| GO | GO:0042025 GO:0020002 GO:0072494 GO:0019013 GO:0055036 GO:0003723 GO:0005198 GO:0008270 GO:0030260 GO:0075713 GO:0075733 GO:0006278 GO:0019061 GO:0039702 GO:0019058 GO:0016032 GO:0019082 GO:0019076 GO:0019068 | |
| Gene3D | 1.10.1200.30 1.10.150.90 1.10.375.10 4.10.60.10 | |
| InterPro | IPR000721 IPR014817 IPR000071 IPR012344 IPR008916 IPR008919 IPR010999 IPR001878 | |
| Pfam | PF00540 PF00607 PF08705 PF00098 | |
| PRINTS | PR00234 | |
| SMART | SM00343 | |
| SUPFAM | SSF47353 SSF47836 SSF47943 SSF57756 | |
| PROSITE | PS50158 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005730 |
nucleolus |
ECO:0000314 |
C |
Figure 1E |
complete | |||||
| GO:0031965 |
nuclear membrane |
ECO:0000314 |
C |
Figure1D |
complete | |||||
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
Figure 1B and C |
complete | |||||
|
involved_in |
GO:0039702 |
viral budding via host ESCRT complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039702 |
viral budding via host ESCRT complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075733 |
intracellular transport of virus |
Reactome:R-HSA-174490 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0075713 |
establishment of integrated proviral latency |
Reactome:R-HSA-175567 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0051169 |
nuclear transport |
Reactome:R-HSA-162590 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030260 |
entry into host cell |
Reactome:R-HSA-173107 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019082 |
viral protein processing |
Reactome:R-HSA-174495 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019068 |
virion assembly |
Reactome:R-HSA-175474 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019064 |
fusion of virus membrane with host plasma membrane |
Reactome:R-HSA-164524 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019061 |
uncoating of virus |
Reactome:R-HSA-173771 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0019058 |
viral life cycle |
Reactome:R-HSA-162588 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006278 |
RNA-dependent DNA biosynthetic process |
Reactome:R-HSA-182876 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
|
part_of |
GO:0019013 |
viral nucleocapsid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0020002 |
host cell plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046755 |
viral budding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019028 |
viral capsid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033644 |
host cell membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044174 |
host cell endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039702 |
viral budding via host ESCRT complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0055036 |
virion membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0072494 |
host multivesicular body |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Yu, KL et al. (2016) HIV-1 nucleocapsid protein localizes efficiently to the nucleus and nucleolus. Virology 492 204-212 PubMed GONUTS page
- ↑ Strack, B et al. (2003) AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Cell 114 689-99 PubMed GONUTS page
- ↑ Demirov, DG et al. (2002) Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function. Proc. Natl. Acad. Sci. U.S.A. 99 955-60 PubMed GONUTS page
h
n
r
v
- GO:0046755 ! viral budding
- GO:0039702 ! viral budding via host ESCRT complex
- GO:0019028 ! viral capsid
- GO:0019058 ! viral life cycle
- GO:0019013 ! viral nucleocapsid
- GO:0016032 ! viral process
- GO:0019082 ! viral protein processing
- GO:0019012 ! virion
- GO:0019068 ! virion assembly
- GO:0055036 ! virion membrane
- Viruses
