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HV1BR:POL
Contents
| Species (Taxon ID) | Human immunodeficiency virus type 1 group M subtype B (isolateBRU/LAI) (HIV-1). (11686) | |
| Gene Name(s) | gag-pol | |
| Protein Name(s) | Gag-Pol polyprotein
Pr160Gag-Pol Matrix protein p17 MA Capsid protein p24 CA Spacer peptide p2 Nucleocapsid protein p7 NC Transframe peptide TF p6-pol p6* Protease PR Retropepsin Reverse transcriptase/ribonuclease H Exoribonuclease H p66 RT p51 RT p15 Integrase IN | |
| External Links | ||
| UniProt | P03367 | |
| EMBL | K02013 | |
| PDB | 1A8G 1A8K 1A94 1AAQ 1D4S 1D4Y 1DAZ 1DIF 1FQX 1HHP 1HNI 1HPO 1HPX 1HSG 1HVL 1IIQ 1IZI 1LZQ 1M0B 1MRW 1MRX 1MSM 1MSN 1NH0 1RL8 1SDT 1SDU 1SDV 1SGU 1SH9 1SP5 1U8G 1UPJ 1XL2 1XL5 1Z8C 1ZBG 1ZJ7 1ZLF 1ZPK 1ZTZ 2A1E 2AZ8 2AZ9 2AZB 2AZC 2B7Z 2BB9 2FDE 2FND 2HB2 2HB4 2HC0 2HND 2HNY 2IEN 2O4K 2O4L 2O4N 2O4P 2O4S 2P3B 2PK5 2PK6 2PQZ 2PWC 2PWR 2PYM 2PYN 2Q63 2Q64 2QAK 2QCI 2QD6 2QD7 2QD8 2QHC 2QNN 2QNP 2QNQ 2R43 2UPJ 2Z4O 2ZGA 2ZYE 3A2O 3BHE 3BVA 3BVB 3CKT 3DJK 3DK1 3FX5 3GGU 3H5B 3I6O 3I8W 3JVW 3JVY 3JW2 3KDB 3KDC 3KDD 3NDU 3NDW 3NDX 3NLS 3PWM 3PWR 3QBF 3QIH 3QN8 3QP0 3QPJ 3QRM 3QRO 3QRS 3ST5 3T11 3T3C 3TOF 3TOG 3TOH 3TTP 3U7S 3UCB 3UF3 3UFN 3UHL 3VF5 3VF7 3VFB 4DFG 4FAF 4FE6 4FL8 4FLG 4FM6 4GB2 4HDB 4HDF 4HDP 4HE9 4HEG 4HLA 4J54 4J55 4J5J 4JEC 4LL3 7UPJ | |
| PDBsum | 1A8G 1A8K 1A94 1AAQ 1D4S 1D4Y 1DAZ 1DIF 1FQX 1HHP 1HNI 1HPO 1HPX 1HSG 1HVL 1IIQ 1IZI 1LZQ 1M0B 1MRW 1MRX 1MSM 1MSN 1NH0 1RL8 1SDT 1SDU 1SDV 1SGU 1SH9 1SP5 1U8G 1UPJ 1XL2 1XL5 1Z8C 1ZBG 1ZJ7 1ZLF 1ZPK 1ZTZ 2A1E 2AZ8 2AZ9 2AZB 2AZC 2B7Z 2BB9 2FDE 2FND 2HB2 2HB4 2HC0 2HND 2HNY 2IEN 2O4K 2O4L 2O4N 2O4P 2O4S 2P3B 2PK5 2PK6 2PQZ 2PWC 2PWR 2PYM 2PYN 2Q63 2Q64 2QAK 2QCI 2QD6 2QD7 2QD8 2QHC 2QNN 2QNP 2QNQ 2R43 2UPJ 2Z4O 2ZGA 2ZYE 3A2O 3BHE 3BVA 3BVB 3CKT 3DJK 3DK1 3FX5 3GGU 3H5B 3I6O 3I8W 3JVW 3JVY 3JW2 3KDB 3KDC 3KDD 3NDU 3NDW 3NDX 3NLS 3PWM 3PWR 3QBF 3QIH 3QN8 3QP0 3QPJ 3QRM 3QRO 3QRS 3ST5 3T11 3T3C 3TOF 3TOG 3TOH 3TTP 3U7S 3UCB 3UF3 3UFN 3UHL 3VF5 3VF7 3VFB 4DFG 4FAF 4FE6 4FL8 4FLG 4FM6 4GB2 4HDB 4HDF 4HDP 4HE9 4HEG 4HLA 4J54 4J55 4J5J 4JEC 4LL3 7UPJ | |
| ProteinModelPortal | P03367 | |
| SMR | P03367 | |
| IntAct | P03367 | |
| MINT | MINT-1506499 | |
| EvolutionaryTrace | P03367 | |
| Proteomes | UP000007692 | |
| GO | GO:0030430 GO:0042025 GO:0020002 GO:0016020 GO:0019013 GO:0004190 GO:0003677 GO:0003887 GO:0004533 GO:0003723 GO:0003964 GO:0004523 GO:0005198 GO:0008270 GO:0015074 GO:0006310 GO:0075713 GO:0039651 GO:0039657 GO:0046718 GO:0075732 GO:0019076 | |
| Gene3D | 1.10.10.200 1.10.1200.30 1.10.150.90 1.10.375.10 2.30.30.10 2.40.70.10 3.30.420.10 4.10.60.10 | |
| InterPro | IPR001969 IPR000721 IPR001037 IPR001584 IPR017856 IPR003308 IPR000071 IPR012344 IPR018061 IPR001995 IPR021109 IPR008916 IPR008919 IPR010999 IPR012337 IPR002156 IPR000477 IPR010659 IPR010661 IPR001878 | |
| Pfam | PF00540 PF00607 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | |
| PRINTS | PR00234 | |
| SMART | SM00343 | |
| SUPFAM | SSF46919 SSF47353 SSF47836 SSF47943 SSF50122 SSF50630 SSF53098 SSF57756 | |
| PROSITE | PS50175 PS00141 PS50994 PS51027 PS50879 PS50878 PS50158 PS50876 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004519 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004518 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004523 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090503 |
RNA phosphodiester bond hydrolysis, exonucleolytic |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004533 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001037 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003964 |
RNA-directed DNA polymerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004523 |
RNA-DNA hybrid ribonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006278 |
RNA-dependent DNA biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015074 |
DNA integration |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003964 |
RNA-directed DNA polymerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004533 |
exoribonuclease H activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019013 |
viral nucleocapsid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0020002 |
host cell plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039526 |
modulation by virus of host apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044826 |
viral genome integration into host DNA |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075713 |
establishment of integrated proviral latency |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075732 |
viral penetration into host nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033644 |
host cell membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039651 |
induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019028 |
viral capsid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039657 |
suppression by virus of host gene expression |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004518 |
nuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008289 |
lipid binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004190 |
aspartic-type endopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004519 |
endonuclease activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003964 |
RNA-directed DNA polymerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044174 |
host cell endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015074 |
DNA integration |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0055036 |
virion membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0072494 |
host multivesicular body |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
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