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HUMAN:WNT5B

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) WNT5B
Protein Name(s) Protein Wnt-5b
External Links
UniProt Q9H1J7
EMBL AY009399
AB060966
AK290430
CH471116
CH471116
BC001749
CCDS CCDS8510.1
RefSeq NP_110402.2
NP_116031.1
UniGene Hs.306051
ProteinModelPortal Q9H1J7
SMR Q9H1J7
BioGrid 123348
IntAct Q9H1J7
MINT MINT-1485183
STRING 9606.ENSP00000308887
PhosphoSite Q9H1J7
DMDM 20532427
MaxQB Q9H1J7
PaxDb Q9H1J7
PRIDE Q9H1J7
DNASU 81029
Ensembl ENST00000310594
ENST00000397196
ENST00000537031
GeneID 81029
KEGG hsa:81029
UCSC uc001qjj.3
CTD 81029
GeneCards GC12P001639
HGNC HGNC:16265
MIM 606361
neXtProt NX_Q9H1J7
PharmGKB PA38104
eggNOG NOG284879
GeneTree ENSGT00760000118943
HOGENOM HOG000039529
HOVERGEN HBG001595
InParanoid Q9H1J7
KO K00444
OMA LTDANSW
PhylomeDB Q9H1J7
TreeFam TF105310
Reactome REACT_163710
REACT_172581
ChiTaRS WNT5B
GeneWiki WNT5B
GenomeRNAi 81029
NextBio 71352
PRO PR:Q9H1J7
Proteomes UP000005640
Bgee Q9H1J7
CleanEx HS_WNT5B
ExpressionAtlas Q9H1J7
Genevestigator Q9H1J7
GO GO:0009986
GO:0005788
GO:0005576
GO:0005615
GO:0070062
GO:0005796
GO:0005886
GO:0005578
GO:0005109
GO:0005102
GO:0045165
GO:0071300
GO:0002062
GO:0045444
GO:0070307
GO:0090090
GO:0030182
GO:0030335
GO:0045600
GO:0016055
GO:0042060
InterPro IPR005817
IPR026537
IPR018161
PANTHER PTHR12027
PTHR12027:SF87
Pfam PF00110
PRINTS PR01349
SMART SM00097
PROSITE PS00246

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

colocalizes_with

GO:0062023

collagen-containing extracellular matrix

PMID:28327460[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(CL:0002551)

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:19056867[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001088)

Seeded From UniProt

complete

involved_in

GO:0070307

lens fiber cell development

PMID:16258938[3]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3L255

P

Seeded From UniProt

complete

involved_in

GO:0071300

cellular response to retinoic acid

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P56706

P

Seeded From UniProt

complete

involved_in

GO:0045444

fat cell differentiation

PMID:19577541[4]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

PMID:19486338[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P56706

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:15135146[6]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:19486338[5]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q01974

F

Seeded From UniProt

complete

involved_in

GO:0002062

chondrocyte differentiation

PMID:15135146[6]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045165

cell fate commitment

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98957
PANTHER:PTN000246517
UniProtKB:P49339
ZFIN:ZDB-GENE-980526-332

P

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000246517
RGD:69250
UniProtKB:P56706
UniProtKB:Q98SN7

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010194
MGI:MGI:108061
MGI:MGI:1197020
MGI:MGI:98953
MGI:MGI:98954
MGI:MGI:98956
MGI:MGI:98958
MGI:MGI:98960
MGI:MGI:98961
MGI:MGI:98962
PANTHER:PTN000246517
UniProtKB:P41221
UniProtKB:Q98SN7
WB:WBGene00000858
WB:WBGene00003029
ZFIN:ZDB-GENE-980526-332

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004009
MGI:MGI:98956
MGI:MGI:98957
PANTHER:PTN000246517
RGD:1311441
RGD:69250
UniProtKB:P41221
UniProtKB:P56704
UniProtKB:P56705
UniProtKB:Q2LMP1
UniProtKB:Q9UBV4
UniProtKB:Q9YGX6

C

Seeded From UniProt

complete

enables

GO:0005109

frizzled binding

PMID:21873635[7]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004009
FB:FBgn0004360
FB:FBgn0010453
FB:FBgn0038134
MGI:MGI:98956
MGI:MGI:98957
MGI:MGI:98958
MGI:MGI:98961
MGI:MGI:98962
PANTHER:PTN000246517
RGD:69079
UniProtKB:P09544
UniProtKB:P41221
UniProtKB:P56703
UniProtKB:Q98SN7

F

Seeded From UniProt

complete

involved_in

GO:0042060

wound healing

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:B1WBR9
ensembl:ENSRNOP00000070168

P

Seeded From UniProt

complete

involved_in

GO:0090090

negative regulation of canonical Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22726
ensembl:ENSMUSP00000137065

P

Seeded From UniProt

complete

involved_in

GO:0045600

positive regulation of fat cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22726
ensembl:ENSMUSP00000137065

P

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22726
ensembl:ENSMUSP00000137065

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22726
ensembl:ENSMUSP00000137065

C

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22726
ensembl:ENSMUSP00000137065

F

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817

P

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

Reactome:R-HSA-3781941

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030666

endocytic vesicle membrane

Reactome:R-HSA-3781943
Reactome:R-HSA-3781941

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

Reactome:R-HSA-195721

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-3781943
Reactome:R-HSA-3247844
Reactome:R-HSA-3247843

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

part_of

GO:0005796

Golgi lumen

Reactome:R-HSA-3247844
Reactome:R-HSA-3247840
Reactome:R-HSA-3247837

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

Reactome:R-HSA-3247837

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-3247843

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Ragelle, H et al. (2017) Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials 128 147-159 PubMed GONUTS page
  2. ↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
  3. ↑ Fokina, VM & Frolova, EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev. Dyn. 235 496-505 PubMed GONUTS page
  4. ↑ van Tienen, FH et al. (2009) Wnt5b stimulates adipogenesis by activating PPARgamma, and inhibiting the beta-catenin dependent Wnt signaling pathway together with Wnt5a. Biochem. Biophys. Res. Commun. 387 207-11 PubMed GONUTS page
  5. ↑ 5.0 5.1 Morioka, K et al. (2009) Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma. Cancer Sci. 100 1227-33 PubMed GONUTS page
  6. ↑ 6.0 6.1 Yates, KE (2004) Demineralized bone alters expression of Wnt network components during chondroinduction of post-natal fibroblasts. Osteoarthr. Cartil. 12 497-505 PubMed GONUTS page
  7. ↑ 7.0 7.1 7.2 7.3 7.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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