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HUMAN:TSG6
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | TNFAIP6 (synonyms: TSG6) | |
Protein Name(s) | Tumor necrosis factor-inducible gene 6 protein
Hyaluronate-binding protein TNF-stimulated gene 6 protein TSG-6 Tumor necrosis factor alpha-induced protein 6 TNF alpha-induced protein 6 | |
External Links | ||
UniProt | P98066 | |
EMBL | M31165 AJ421518 AJ419936 AC009311 CH471058 BC030205 | |
CCDS | CCDS2193.1 | |
PIR | A41735 | |
RefSeq | NP_009046.2 | |
UniGene | Hs.437322 | |
PDB | 1O7B 1O7C 2PF5 2WNO | |
PDBsum | 1O7B 1O7C 2PF5 2WNO | |
ProteinModelPortal | P98066 | |
SMR | P98066 | |
BioGrid | 112984 | |
STRING | 9606.ENSP00000243347 | |
DrugBank | DB08818 | |
PhosphoSite | P98066 | |
DMDM | 68067717 | |
PaxDb | P98066 | |
PRIDE | P98066 | |
DNASU | 7130 | |
Ensembl | ENST00000243347 | |
GeneID | 7130 | |
KEGG | hsa:7130 | |
UCSC | uc002txk.3 | |
CTD | 7130 | |
GeneCards | GC02P152178 | |
HGNC | HGNC:11898 | |
HPA | CAB032719 HPA007896 | |
MIM | 600410 | |
neXtProt | NX_P98066 | |
PharmGKB | PA36595 | |
eggNOG | NOG237473 | |
GeneTree | ENSGT00730000110695 | |
HOGENOM | HOG000043074 | |
HOVERGEN | HBG006669 | |
InParanoid | P98066 | |
OMA | KECGGVF | |
OrthoDB | EOG7Q5HF0 | |
PhylomeDB | P98066 | |
TreeFam | TF334173 | |
EvolutionaryTrace | P98066 | |
GeneWiki | TSG-6 | |
GenomeRNAi | 7130 | |
NextBio | 27899 | |
PRO | PR:P98066 | |
Proteomes | UP000005640 | |
Bgee | P98066 | |
CleanEx | HS_TNFAIP6 | |
Genevestigator | P98066 | |
GO | GO:0005615 GO:0005540 GO:0007155 GO:0007267 GO:0006954 GO:0030728 GO:0030335 GO:0007165 | |
Gene3D | 2.60.120.290 3.10.100.10 | |
InterPro | IPR016186 IPR016187 IPR000859 IPR000538 | |
Pfam | PF00431 PF00193 | |
PRINTS | PR01265 | |
SMART | SM00042 SM00445 | |
SUPFAM | SSF49854 SSF56436 | |
PROSITE | PS01180 PS01241 PS50963 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0050728 |
negative regulation of inflammatory response |
ECO:0000314 |
P |
Fig.7 |
complete | |||||
involved_in |
GO:0050728 |
negative regulation of inflammatory response |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050728 |
negative regulation of inflammatory response |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002930557 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002930557 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030728 |
ovulation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R4G8 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030335 |
positive regulation of cell migration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R4G8 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:M0R4G8 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005540 |
hyaluronic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007155 |
cell adhesion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007267 |
cell-cell signaling |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007165 |
signal transduction |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005540 |
hyaluronic acid binding |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:1904813 |
ficolin-1-rich granule lumen |
Reactome:R-HSA-6800434 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:1904724 |
tertiary granule lumen |
Reactome:R-HSA-6798745 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043312 |
neutrophil degranulation |
Reactome:R-HSA-6798695 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-6800434 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0007155 |
cell adhesion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Danchuk, S et al. (2011) Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6. Stem Cell Res Ther 2 27 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Lee, TH et al. (1992) A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44. J. Cell Biol. 116 545-57 PubMed GONUTS page