GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:TSG6

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) TNFAIP6 (synonyms: TSG6)
Protein Name(s) Tumor necrosis factor-inducible gene 6 protein

Hyaluronate-binding protein TNF-stimulated gene 6 protein TSG-6 Tumor necrosis factor alpha-induced protein 6 TNF alpha-induced protein 6

External Links
UniProt P98066
EMBL M31165
AJ421518
AJ419936
AC009311
CH471058
BC030205
CCDS CCDS2193.1
PIR A41735
RefSeq NP_009046.2
UniGene Hs.437322
PDB 1O7B
1O7C
2PF5
2WNO
PDBsum 1O7B
1O7C
2PF5
2WNO
ProteinModelPortal P98066
SMR P98066
BioGrid 112984
STRING 9606.ENSP00000243347
DrugBank DB08818
PhosphoSite P98066
DMDM 68067717
PaxDb P98066
PRIDE P98066
DNASU 7130
Ensembl ENST00000243347
GeneID 7130
KEGG hsa:7130
UCSC uc002txk.3
CTD 7130
GeneCards GC02P152178
HGNC HGNC:11898
HPA CAB032719
HPA007896
MIM 600410
neXtProt NX_P98066
PharmGKB PA36595
eggNOG NOG237473
GeneTree ENSGT00730000110695
HOGENOM HOG000043074
HOVERGEN HBG006669
InParanoid P98066
OMA KECGGVF
OrthoDB EOG7Q5HF0
PhylomeDB P98066
TreeFam TF334173
EvolutionaryTrace P98066
GeneWiki TSG-6
GenomeRNAi 7130
NextBio 27899
PRO PR:P98066
Proteomes UP000005640
Bgee P98066
CleanEx HS_TNFAIP6
Genevestigator P98066
GO GO:0005615
GO:0005540
GO:0007155
GO:0007267
GO:0006954
GO:0030728
GO:0030335
GO:0007165
Gene3D 2.60.120.290
3.10.100.10
InterPro IPR016186
IPR016187
IPR000859
IPR000538
Pfam PF00431
PF00193
PRINTS PR01265
SMART SM00042
SM00445
SUPFAM SSF49854
SSF56436
PROSITE PS01180
PS01241
PS50963

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050728

negative regulation of inflammatory response

PMID:21569482[1]

ECO:0000314

P

Fig.7

complete
CACAO 3519

involved_in

GO:0050728

negative regulation of inflammatory response

PMID:21569482[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050728

negative regulation of inflammatory response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002930557
UniProtKB:P98066

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002930557
RGD:621359

C

Seeded From UniProt

complete

involved_in

GO:0030728

ovulation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:M0R4G8
ensembl:ENSRNOP00000064253

P

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:M0R4G8
ensembl:ENSRNOP00000064253

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:M0R4G8
ensembl:ENSRNOP00000064253

C

Seeded From UniProt

complete

enables

GO:0005540

hyaluronic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000538

F

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000538

P

Seeded From UniProt

complete

involved_in

GO:0007267

cell-cell signaling

PMID:1730767[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

PMID:1730767[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

PMID:1730767[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005540

hyaluronic acid binding

PMID:1730767[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:1904813

ficolin-1-rich granule lumen

Reactome:R-HSA-6800434

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:1904724

tertiary granule lumen

Reactome:R-HSA-6798745

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043312

neutrophil degranulation

Reactome:R-HSA-6798695

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-6800434
Reactome:R-HSA-6798745

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Danchuk, S et al. (2011) Human multipotent stromal cells attenuate lipopolysaccharide-induced acute lung injury in mice via secretion of tumor necrosis factor-α-induced protein 6. Stem Cell Res Ther 2 27 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Lee, TH et al. (1992) A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44. J. Cell Biol. 116 545-57 PubMed GONUTS page