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HUMAN:TILB
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | LRRC6 (synonyms: LRTP, TSLRP) | |
| Protein Name(s) | Protein tilB homolog
Leucine-rich repeat-containing protein 6 Leucine-rich testis-specific protein Testis-specific leucine-rich repeat protein | |
| External Links | ||
| UniProt | Q86X45 | |
| EMBL | U60666 BC027589 BC047286 | |
| CCDS | CCDS6365.1 | |
| RefSeq | NP_036604.2 | |
| UniGene | Hs.591865 | |
| ProteinModelPortal | Q86X45 | |
| SMR | Q86X45 | |
| BioGrid | 117167 | |
| IntAct | Q86X45 | |
| PhosphoSite | Q86X45 | |
| DMDM | 134047813 | |
| PaxDb | Q86X45 | |
| PRIDE | Q86X45 | |
| Ensembl | ENST00000519595 ENST00000620350 | |
| GeneID | 23639 | |
| KEGG | hsa:23639 | |
| UCSC | uc003ytk.4 | |
| CTD | 23639 | |
| GeneCards | GC08M133584 | |
| GeneReviews | LRRC6 | |
| HGNC | HGNC:16725 | |
| HPA | HPA021640 HPA028058 | |
| MIM | 614930 614935 | |
| neXtProt | NX_Q86X45 | |
| Orphanet | 244 | |
| PharmGKB | PA134921522 | |
| eggNOG | NOG294986 | |
| GeneTree | ENSGT00720000108813 | |
| HOGENOM | HOG000258801 | |
| HOVERGEN | HBG053229 | |
| InParanoid | Q86X45 | |
| OMA | KSEHCPE | |
| OrthoDB | EOG7KM5T7 | |
| PhylomeDB | Q86X45 | |
| TreeFam | TF324815 | |
| ChiTaRS | LRRC6 | |
| GenomeRNAi | 23639 | |
| NextBio | 46433 | |
| PRO | PR:Q86X45 | |
| Proteomes | UP000005640 | |
| Bgee | Q86X45 | |
| CleanEx | HS_LRRC6 | |
| ExpressionAtlas | Q86X45 | |
| Genevestigator | Q86X45 | |
| GO | GO:0005929 GO:0005737 GO:0003341 GO:0060287 GO:0036159 GO:0008584 GO:0044458 GO:0036158 GO:0061458 GO:0030317 | |
| InterPro | IPR007052 IPR001611 IPR003603 | |
| SMART | SM00446 | |
| PROSITE | PS51203 PS51450 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0030030 |
cell projection organization |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0071840 |
cellular component organization or biogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0042384 |
cilium assembly |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0070286 |
axonemal dynein complex assembly |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0043933 |
macromolecular complex subunit organization |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0071822 |
protein complex subunit organization |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0070271 |
protein complex biogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0006461 |
protein complex assembly |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0034622 |
cellular macromolecular complex assembly |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0030030 |
cell projection organization |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0044085 |
cellular component biogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0022607 |
cellular component assembly |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0032989 |
cellular component morphogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0048858 |
cell projection morphogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0060271 |
cilium morphogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0010927 |
cellular component assembly involved in morphogenesis |
ECO:0000314 |
P |
Ruth |
complete | |||||
| GO:0043623 |
cellular protein complex assembly |
ECO:0000314 |
P |
Ruth |
complete | |||||
|
involved_in |
GO:0061458 |
reproductive system development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060287 |
epithelial cilium movement involved in determination of left/right asymmetry |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044458 |
motile cilium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0036159 |
inner dynein arm assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0036158 |
outer dynein arm assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030317 |
flagellated sperm motility |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008584 |
male gonad development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005929 |
cilium |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0003341 |
cilium movement |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060294 |
cilium movement involved in cell motility |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002705561 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060271 |
cilium assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1915134 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0044458 |
motile cilium assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002705561 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031514 |
motile cilium |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0014395 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007010 |
cytoskeleton organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002705561 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005929 |
cilium |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002705561 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0014395 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0003351 |
epithelial cilium movement |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000833862 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008584 |
male gonad development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O88978 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O88978 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005929 |
cilium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Rauramo, L et al. (1975) The effect of castration and peroral estrogen therapy on some psychological functions. Front Horm Res 3 94-104 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Hattori, M et al. (1975) Poly(8-aminoguanylic acid): formation of ordered self-structures and interaction with poly(cytidylic acid). Biochemistry 14 5033-45 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Sanner, T (1975) Formation of transient complexes in the glutamate dehydrogenase catalyzed reaction. Biochemistry 14 5094-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Kott, E et al. (2012) Loss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesia. Am. J. Hum. Genet. 91 958-64 PubMed GONUTS page
- ↑ 5.0 5.1 Xue, JC & Goldberg, E (2000) Identification of a novel testis-specific leucine-rich protein in humans and mice. Biol. Reprod. 62 1278-84 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
- Catarrhini
- GO:0032989 ! cellular anatomical entity morphogenesis
- GO:0071840 ! cellular component organization or biogenesis
- GO:0044085 ! cellular component biogenesis
- GO:0010927 ! cellular component assembly involved in morphogenesis
- GO:0022607 ! cellular component assembly
- GO:0043623 ! cellular protein complex assembly
- GO:0034622 ! cellular protein-containing complex assembly
- GO:0042995 ! cell projection
- GO:0048858 ! cell projection morphogenesis
- GO:0030030 ! cell projection organization
- Chordata
- GO:0005929 ! cilium
- GO:0060271 ! cilium assembly
- GO:0042384 ! cilium assembly
- GO:0060294 ! cilium movement involved in cell motility
- GO:0003341 ! cilium movement
- Craniata
- GO:0005737 ! cytoplasm
- GO:0007010 ! cytoskeleton organization
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