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HUMAN:SIL1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SIL1
Protein Name(s) Nucleotide exchange factor SIL1

BiP-associated protein BAP

External Links
UniProt Q9H173
EMBL AJ299442
AF547994
AY358950
AK074624
AK075177
CH471062
CH471062
BC011568
CCDS CCDS4209.1
RefSeq NP_001032722.1
NP_071909.1
UniGene Hs.483521
ProteinModelPortal Q9H173
BioGrid 122145
IntAct Q9H173
MINT MINT-1199811
STRING 9606.ENSP00000265195
PhosphoSite Q9H173
DMDM 74733533
MaxQB Q9H173
PaxDb Q9H173
PRIDE Q9H173
DNASU 64374
Ensembl ENST00000265195
ENST00000394817
GeneID 64374
KEGG hsa:64374
UCSC uc003ldo.3
CTD 64374
GeneCards GC05M138282
GeneReviews SIL1
HGNC HGNC:24624
HPA HPA011949
MIM 248800
608005
neXtProt NX_Q9H173
Orphanet 559
PharmGKB PA142670916
eggNOG NOG310365
GeneTree ENSGT00510000048102
HOGENOM HOG000154326
HOVERGEN HBG093955
InParanoid Q9H173
KO K14001
PhylomeDB Q9H173
TreeFam TF324307
ChiTaRS SIL1
GeneWiki SIL1
GenomeRNAi 64374
NextBio 66295
PRO PR:Q9H173
Proteomes UP000005640
Bgee Q9H173
CleanEx HS_SIL1
ExpressionAtlas Q9H173
Genevestigator Q9H173
GO GO:0005783
GO:0005788
GO:0005615
GO:0051082
GO:0006886
GO:0006457
Gene3D 1.25.10.10
InterPro IPR011989
IPR016024
SUPFAM SSF48371

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005615

extracellular space

PMID:16502470[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001914)

Seeded From UniProt

complete

enables

GO:0051082

unfolded protein binding

PMID:11101517[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006886

intracellular protein transport

PMID:11101517[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

PMID:11101517[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:11101517[2]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1932040
PANTHER:PTN000448398
TAIR:locus:2083800

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000448398
UniProtKB:Q84J81

C

Seeded From UniProt

complete

enables

GO:0000774

adenyl-nucleotide exchange factor activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000448398
SGD:S000000305
SGD:S000005391

F

Seeded From UniProt

complete

involved_in

GO:0050790

regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0000774

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9EPK6
ensembl:ENSMUSP00000025215

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653
UniProtKB-KW:KW-0811

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0096

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Tyson, JR & Stirling, CJ (2000) LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum. EMBO J. 19 6440-52 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page