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HUMAN:S35B4

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SLC35B4 (synonyms: YEA4)
Protein Name(s) UDP-xylose and UDP-N-acetylglucosamine transporter

Solute carrier family 35 member B4 YEA4 homolog

External Links
UniProt Q969S0
EMBL AJ971941
AB052892
AJ315497
AJ315498
AK027603
AK027726
AK075368
AK222874
AC008154
CH236950
CH471070
BC008413
CCDS CCDS34756.1
RefSeq NP_116215.1
UniGene Hs.490181
ProteinModelPortal Q969S0
STRING 9606.ENSP00000367770
TCDB 2.A.7.10.2
DMDM 74751727
MaxQB Q969S0
PaxDb Q969S0
PRIDE Q969S0
Ensembl ENST00000378509
GeneID 84912
KEGG hsa:84912
UCSC uc003vrn.3
uc003vro.4
CTD 84912
GeneCards GC07M133974
HGNC HGNC:20584
HPA HPA049779
MIM 610923
neXtProt NX_Q969S0
PharmGKB PA134922110
eggNOG NOG250393
GeneTree ENSGT00390000002915
HOGENOM HOG000234632
HOVERGEN HBG093926
InParanoid Q969S0
KO K15278
OMA IRYYAVM
OrthoDB EOG7WX08P
PhylomeDB Q969S0
TreeFam TF312926
Reactome REACT_22151
ChiTaRS SLC35B4
GeneWiki SLC35B4
GenomeRNAi 84912
NextBio 75300
PRO PR:Q969S0
Proteomes UP000005640
Bgee Q969S0
CleanEx HS_SLC35B4
ExpressionAtlas Q969S0
Genevestigator Q969S0
GO GO:0005794
GO:0000139
GO:0016021
GO:0005462
GO:0005464
GO:0008643
GO:0006111
GO:0055085
GO:0015788
GO:0015790
InterPro IPR013657
Pfam PF08449

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005783

endoplasmic reticulum

PMID:21918738[1]

ECO:0000314

C

Figure 7 and Figure 8.

complete
CACAO 8424

part_of

GO:0005783

endoplasmic reticulum

PMID:21918738[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015790

UDP-xylose transmembrane transport

PMID:15911612[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1990569

UDP-N-acetylglucosamine transmembrane transport

PMID:15911612[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:15911612[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005464

UDP-xylose transmembrane transporter activity

PMID:15911612[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005462

UDP-N-acetylglucosamine transmembrane transporter activity

PMID:15911612[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0030176

integral component of endoplasmic reticulum membrane

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000081292
TAIR:locus:2012482
TAIR:locus:2058837

C

Seeded From UniProt

complete

part_of

GO:0030173

integral component of Golgi membrane

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000081292
TAIR:locus:2012482
TAIR:locus:2127163
WB:WBGene00004206
WB:WBGene00018827

C

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029849
FB:FBgn0036695
PANTHER:PTN000081292
PomBase:SPBC839.11c
SGD:S000000730
TAIR:locus:2012482
TAIR:locus:2058837
TAIR:locus:2127163
UniProtKB:Q8TB61
UniProtKB:Q969S0
UniProtKB:Q9VEI3
WB:WBGene00004206
WB:WBGene00018827

F

Seeded From UniProt

complete

enables

GO:0005464

UDP-xylose transmembrane transporter activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029849
PANTHER:PTN000845636
UniProtKB:Q969S0

F

Seeded From UniProt

complete

enables

GO:0005462

UDP-N-acetylglucosamine transmembrane transporter activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029849
PANTHER:PTN000081451
SGD:S000000730
UniProtKB:Q969S0

F

Seeded From UniProt

complete

involved_in

GO:0006111

regulation of gluconeogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8CIA5
ensembl:ENSMUSP00000019143

P

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013657

P

Seeded From UniProt

complete

enables

GO:0005464

UDP-xylose transmembrane transporter activity

Reactome:R-HSA-742373

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005462

UDP-N-acetylglucosamine transmembrane transporter activity

Reactome:R-HSA-742354

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

Reactome:R-HSA-742373
Reactome:R-HSA-742354

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0762

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Maszczak-Seneczko, D et al. (2011) Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters. Acta Biochim. Pol. 58 413-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Ashikov, A et al. (2005) The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine. J. Biol. Chem. 280 27230-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page