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HUMAN:Q6GRK0

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) CYP3A4 (ECO:0000313 with EMBL:AAH69418.1)
Protein Name(s) Cytochrome P450 family 3 subfamily A polypeptide 4 (ECO:0000313 with EMBL:ABI96208.1)

Cytochrome P450, family 3, subfamily A, polypeptide 4 (ECO:0000313 with EMBL:AAH69418.1) Cytochrome P450, family 3, subfamily A, polypeptide 4, isoform CRA_a (ECO:0000313 with EMBL:EAW76635.1) Cytochrome P450, subfamily IIIA, polypeptide 4 (ECO:0000313 with EMBL:AAI01632.1) cDNA, FLJ93427, Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4(CYP3A4), transcript variant 1, mRNA (ECO:0000313 with EMBL:BAG35806.1)

External Links
UniProt Q6GRK0
EMBL BC069418
BC101631
DQ005611
DQ924960
AK312967
CH236956
CH471091
RefSeq NP_001189784.1
NP_059488.2
UniGene Hs.728751
SMR Q6GRK0
GeneID 1576
KEGG hsa:1576
CTD 1576
PharmGKB PA130
GeneTree ENSGT00760000118816
HOVERGEN HBG108567
KO K17689
OMA DMECHKK
PhylomeDB Q6GRK0
ChiTaRS CYP3A4
GenomeRNAi 1576
NextBio 6475
GO GO:0020037
GO:0005506
GO:0016712
Gene3D 1.10.630.10
InterPro IPR001128
IPR017972
IPR008072
IPR002402
Pfam PF00067
PRINTS PR00464
PR01689
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0004497

monooxygenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002402

F

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002402
InterPro:IPR008072
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR017972
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016712

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008072

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002402
InterPro:IPR008072
InterPro:IPR036396

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002402
InterPro:IPR008072
InterPro:IPR017972
InterPro:IPR036396

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

Notes

References

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