HUMAN:Q5ZEZ0

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	MSH4 (ECO:0000313 with EMBL:CAH59752.1)
Protein Name(s)	MutS homolog 4 (ECO:0000313 with EMBL:CAH59752.1)
External Links
UniProt	Q5ZEZ0
EMBL	AJ844635
UniGene	Hs.216639
ProteinModelPortal	Q5ZEZ0
ChiTaRS	MSH4
Bgee	Q5ZEZ0
ExpressionAtlas	Q5ZEZ0
GO	GO:0000795 GO:0005524 GO:0030983 GO:0007292 GO:0006298 GO:0001541 GO:0007283 GO:0007129
Gene3D	3.40.50.300
InterPro	IPR000432 IPR027417
Pfam	PF00488

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006298	mismatch repair	PMID:10809667	ECO:0000315			P		Figure 6 shows that apiring occurs in MutS.The comparison of the meiotic phenotype between Msh4−/− mice revealed that both MutS homologs are required in the early stages of meiosis I and are essential for normal chromosome synapsis during zygonema. Figure 5 also shows that follicular development as part of ovarian reorganization were apparent in Msh4+/+ ovaries (Fig. ​(Fig.5C,5C, arrows), whereas many of the oogonia in Msh4−/− cells had already been lost (Fig. ​(Fig.5D).5D). This helps signify mismatch repair is MutS homologs.	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432	F		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432	P		Seeded From UniProt	complete
enables	GO:0030983	mismatched DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000432	F		Seeded From UniProt	complete
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References

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