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HUMAN:PDIA5

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) PDIA5 (synonyms: PDIR)
Protein Name(s) Protein disulfide-isomerase A5

Protein disulfide isomerase-related protein

External Links
UniProt Q14554
EMBL D49490
AC063922
AC083797
CH471052
CH471052
CH471052
CH471052
BC001625
CCDS CCDS3020.1
PIR S66673
RefSeq NP_006801.1
UniGene Hs.477352
PDB 4I6X
PDBsum 4I6X
ProteinModelPortal Q14554
SMR Q14554
BioGrid 116154
IntAct Q14554
MINT MINT-2868874
STRING 9606.ENSP00000323313
PhosphoSite Q14554
DMDM 2501208
MaxQB Q14554
PaxDb Q14554
PRIDE Q14554
Ensembl ENST00000316218
ENST00000489923
GeneID 10954
KEGG hsa:10954
UCSC uc003egc.2
CTD 10954
GeneCards GC03P122785
HGNC HGNC:24811
HPA HPA030353
HPA030354
HPA030355
HPA030356
neXtProt NX_Q14554
PharmGKB PA142671191
eggNOG COG0526
GeneTree ENSGT00730000110455
HOGENOM HOG000039967
HOVERGEN HBG053547
InParanoid Q14554
KO K09583
OMA YYHYGKF
PhylomeDB Q14554
TreeFam TF106379
Reactome REACT_18273
ChiTaRS PDIA5
GenomeRNAi 10954
NextBio 41621
PRO PR:Q14554
Proteomes UP000005640
Bgee Q14554
CleanEx HS_PDIA5
ExpressionAtlas Q14554
Genevestigator Q14554
GO GO:0005783
GO:0005788
GO:0005789
GO:0016491
GO:0003756
GO:0006987
GO:0045454
GO:0044267
GO:0030968
GO:0055114
GO:0006457
GO:0034976
Gene3D 3.40.30.10
InterPro IPR012336
IPR017937
IPR013766
Pfam PF00085
SUPFAM SSF52833
PROSITE PS00014
PS00194
PS51352

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0015037

peptide disulfide oxidoreductase activity

PMID:16677074[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045454

cell redox homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013766
InterPro:IPR017937

P

Seeded From UniProt

complete

enables

GO:0003756

protein disulfide isomerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.3.4.1

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

PMID:7556671[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

PMID:7556671[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

PMID:7556671[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

PMID:7556671[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003756

protein disulfide isomerase activity

PMID:7556671[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0036498

IRE1-mediated unfolded protein response

Reactome:R-HSA-381070

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

Reactome:R-HSA-1791122

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0096

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Alanen, HI et al. () pH dependence of the peptide thiol-disulfide oxidase activity of six members of the human protein disulfide isomerase family. Antioxid. Redox Signal. 8 283-91 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Hayano, T & Kikuchi, M (1995) Molecular cloning of the cDNA encoding a novel protein disulfide isomerase-related protein (PDIR). FEBS Lett. 372 210-4 PubMed GONUTS page