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HUMAN:PDIA2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | PDIA2 (synonyms: PDIP) | |
| Protein Name(s) | Protein disulfide-isomerase A2
Pancreas-specific protein disulfide isomerase PDIp | |
| External Links | ||
| UniProt | Q13087 | |
| EMBL | AB127078 AE006463 Z69667 Z69667 CH471112 BC000537 BC075029 U19948 AK295383 | |
| CCDS | CCDS42089.1 | |
| RefSeq | NP_006840.2 | |
| UniGene | Hs.66581 | |
| ProteinModelPortal | Q13087 | |
| SMR | Q13087 | |
| BioGrid | 122240 | |
| IntAct | Q13087 | |
| MINT | MINT-1513985 | |
| STRING | 9606.ENSP00000219406 | |
| PhosphoSite | Q13087 | |
| DMDM | 21264492 | |
| MaxQB | Q13087 | |
| PaxDb | Q13087 | |
| PRIDE | Q13087 | |
| DNASU | 64714 | |
| Ensembl | ENST00000219406 ENST00000404312 | |
| GeneID | 64714 | |
| KEGG | hsa:64714 | |
| UCSC | uc002cgn.1 | |
| CTD | 64714 | |
| GeneCards | GC16P000336 | |
| H-InvDB | HIX0202311 | |
| HGNC | HGNC:14180 | |
| HPA | HPA051692 HPA053492 | |
| MIM | 608012 | |
| neXtProt | NX_Q13087 | |
| PharmGKB | PA33153 | |
| eggNOG | COG0526 | |
| GeneTree | ENSGT00760000119201 | |
| HOVERGEN | HBG005920 | |
| InParanoid | Q13087 | |
| KO | K09581 | |
| OMA | QEVPPDW | |
| OrthoDB | EOG7VHSX1 | |
| PhylomeDB | Q13087 | |
| TreeFam | TF106381 | |
| BRENDA | 5.3.4.1 | |
| GenomeRNAi | 64714 | |
| NextBio | 66651 | |
| PRO | PR:Q13087 | |
| Proteomes | UP000005640 | |
| Bgee | Q13087 | |
| CleanEx | HS_PDIA2 | |
| ExpressionAtlas | Q13087 | |
| Genevestigator | Q13087 | |
| GO | GO:0005783 GO:0005788 GO:0003756 GO:0005496 GO:0045454 GO:0019511 GO:0006457 GO:0006621 GO:1902175 GO:0034976 | |
| Gene3D | 3.40.30.10 | |
| InterPro | IPR005792 IPR012336 IPR017937 IPR013766 | |
| Pfam | PF00085 | |
| SUPFAM | SSF52833 | |
| TIGRFAMs | TIGR01130 | |
| PROSITE | PS00014 PS00194 PS51352 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0015037 |
peptide disulfide oxidoreductase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034976 |
response to endoplasmic reticulum stress |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000432607 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000432607 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0014002 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015036 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015037 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045454 |
cell redox homeostasis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015036 |
disulfide oxidoreductase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034975 |
protein folding in endoplasmic reticulum |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006621 |
protein retention in ER lumen |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008289 |
lipid binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005496 |
steroid binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005788 |
endoplasmic reticulum lumen |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Alanen, HI et al. () pH dependence of the peptide thiol-disulfide oxidase activity of six members of the human protein disulfide isomerase family. Antioxid. Redox Signal. 8 283-91 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 Hetz, C et al. (2011) The unfolded protein response: integrating stress signals through the stress sensor IRE1α. Physiol. Rev. 91 1219-43 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Desilva, MG et al. (1996) Characterization and chromosomal localization of a new protein disulfide isomerase, PDIp, highly expressed in human pancreas. DNA Cell Biol. 15 9-16 PubMed GONUTS page
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