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HUMAN:MURC
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MURC | |
| Protein Name(s) | Muscle-related coiled-coil protein
Muscle-restricted coiled-coil protein | |
| External Links | ||
| UniProt | Q5BKX8 | |
| EMBL | EU487253 AK300099 AL354917 BC090888 | |
| CCDS | CCDS35083.1 | |
| RefSeq | NP_001018126.1 | |
| UniGene | Hs.733374 Hs.99004 | |
| ProteinModelPortal | Q5BKX8 | |
| BioGrid | 131419 | |
| STRING | 9606.ENSP00000418668 | |
| PhosphoSite | Q5BKX8 | |
| DMDM | 172045939 | |
| PaxDb | Q5BKX8 | |
| PRIDE | Q5BKX8 | |
| Ensembl | ENST00000307584 | |
| GeneID | 347273 | |
| KEGG | hsa:347273 | |
| UCSC | uc004bba.3 | |
| CTD | 347273 | |
| GeneCards | GC09P103341 | |
| H-InvDB | HIX0025822 HIX0169332 | |
| HGNC | HGNC:33742 | |
| HPA | HPA020973 HPA020987 HPA021021 | |
| neXtProt | NX_Q5BKX8 | |
| PharmGKB | PA164723237 | |
| eggNOG | NOG25053 | |
| GeneTree | ENSGT00530000063058 | |
| HOGENOM | HOG000293135 | |
| InParanoid | Q5BKX8 | |
| OMA | DRNLTEN | |
| OrthoDB | EOG7JDQZ7 | |
| PhylomeDB | Q5BKX8 | |
| TreeFam | TF331031 | |
| ChiTaRS | MURC | |
| GenomeRNAi | 347273 | |
| NextBio | 99080 | |
| PRO | PR:Q5BKX8 | |
| Proteomes | UP000005640 | |
| Bgee | Q5BKX8 | |
| Genevestigator | Q5BKX8 | |
| GO | GO:0030018 GO:0030154 GO:0007517 GO:0045944 GO:0006351 | |
| InterPro | IPR026752 | |
| PANTHER | PTHR15240 | |
| Pfam | PF15237 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0010468 |
regulation of gene expression |
ECO:0000315 |
P |
Fig 3. |
complete | |||||
|
part_of |
GO:0005901 |
caveola |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010468 |
regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1915266 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A2AMM0 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030018 |
Z disc |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A2AMM0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005901 |
caveola |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A2AMM0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A2AMM0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A2AMM0 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005901 |
caveola |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:B1PRL5 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:B1PRL5 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035023 |
regulation of Rho protein signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007517 |
muscle organ development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042383 |
sarcolemma |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005901 |
caveola |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030017 |
sarcomere |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Rodriguez, G et al. (2011) Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy. Circ Cardiovasc Genet 4 349-58 PubMed GONUTS page
- ↑ Hansen, CG et al. (2009) SDPR induces membrane curvature and functions in the formation of caveolae. Nat. Cell Biol. 11 807-14 PubMed GONUTS page
- ↑ Naito, D et al. (2015) The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol. 309 H2127-36 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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