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HUMAN:HIRP3
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | HIRIP3 | |
| Protein Name(s) | HIRA-interacting protein 3 | |
| External Links | ||
| UniProt | Q9BW71 | |
| EMBL | AJ223349 AJ223350 AJ223351 BX393533 AC093512 BC000588 | |
| CCDS | CCDS10664.1 CCDS58449.1 | |
| RefSeq | NP_001184252.1 NP_003600.2 | |
| UniGene | Hs.567370 | |
| ProteinModelPortal | Q9BW71 | |
| BioGrid | 114053 | |
| IntAct | Q9BW71 | |
| MINT | MINT-1411245 | |
| STRING | 9606.ENSP00000279392 | |
| PhosphoSite | Q9BW71 | |
| DMDM | 116242511 | |
| MaxQB | Q9BW71 | |
| PaxDb | Q9BW71 | |
| PRIDE | Q9BW71 | |
| Ensembl | ENST00000279392 ENST00000564026 | |
| GeneID | 8479 | |
| KEGG | hsa:8479 | |
| UCSC | uc002dve.3 | |
| CTD | 8479 | |
| GeneCards | GC16M030005 | |
| HGNC | HGNC:4917 | |
| MIM | 603365 | |
| neXtProt | NX_Q9BW71 | |
| PharmGKB | PA29294 | |
| eggNOG | NOG25729 | |
| GeneTree | ENSGT00390000014062 | |
| HOGENOM | HOG000112903 | |
| HOVERGEN | HBG066199 | |
| InParanoid | Q9BW71 | |
| OMA | CHSHKER | |
| OrthoDB | EOG790G1V | |
| PhylomeDB | Q9BW71 | |
| TreeFam | TF331753 | |
| GeneWiki | HIRIP3 | |
| GenomeRNAi | 8479 | |
| NextBio | 31725 | |
| PRO | PR:Q9BW71 | |
| Proteomes | UP000005640 | |
| Bgee | Q9BW71 | |
| CleanEx | HS_HIRIP3 | |
| ExpressionAtlas | Q9BW71 | |
| Genevestigator | Q9BW71 | |
| GO | GO:0005730 GO:0005654 GO:0005634 GO:0006333 | |
| InterPro | IPR019098 | |
| Pfam | PF09649 | |
| SMART | SM01082 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005654 |
nucleoplasm |
ECO:0000314 |
C |
Figure 3.b. and 3.c. indicate that four HIRIP3 siRNA causes HR defect. Even though these HIRIP3 siRNA are also correlated with off target Rad51 depletion, only siHIRIP3-5 had 7 nucleotide seed match to 3‘UTR Rad51 off-targeting. Therefore, HR defects are 3-fold enriched for antisense seed sequence complementary to Rad51. However, Figure 3.b. also indicates three siRNAs defect HR depleted Rad51 without full seed complementary to the 3’UTR. Therefore, HIRIP3 siRNAs can change the mechanisms of Rad51 off-targeting. |
complete | |||||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005730 |
nucleolus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006333 |
chromatin assembly or disassembly |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Adamson, B et al. (2012) A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat. Cell Biol. 14 318-28 PubMed GONUTS page
- ↑ Assrir, N et al. (2007) HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2. Biol. Chem. 388 391-8 PubMed GONUTS page
- ↑ 3.0 3.1 Lorain, S et al. (1998) Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA. Mol. Cell. Biol. 18 5546-56 PubMed GONUTS page
