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HUMAN:FASTK
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | FASTK | |
| Protein Name(s) | Fas-activated serine/threonine kinase
FAST kinase | |
| External Links | ||
| UniProt | Q14296 | |
| EMBL | X86779 AK292232 AB209783 AC010973 CH471173 CH471173 BC011770 BC039026 | |
| CCDS | CCDS59088.1 CCDS5918.1 CCDS5919.1 | |
| PIR | I37386 | |
| RefSeq | NP_001245390.1 NP_006703.1 NP_148936.2 | |
| UniGene | Hs.647094 | |
| ProteinModelPortal | Q14296 | |
| BioGrid | 116126 | |
| IntAct | Q14296 | |
| STRING | 9606.ENSP00000297532 | |
| PhosphoSite | Q14296 | |
| DMDM | 13124202 | |
| MaxQB | Q14296 | |
| PaxDb | Q14296 | |
| PRIDE | Q14296 | |
| DNASU | 10922 | |
| Ensembl | ENST00000297532 ENST00000353841 ENST00000482571 | |
| GeneID | 10922 | |
| KEGG | hsa:10922 | |
| UCSC | uc003wiw.1 uc003wiy.2 | |
| CTD | 10922 | |
| GeneCards | GC07M150773 | |
| HGNC | HGNC:24676 | |
| HPA | CAB032539 HPA031621 | |
| MIM | 606965 | |
| neXtProt | NX_Q14296 | |
| PharmGKB | PA142671775 | |
| eggNOG | NOG47372 | |
| GeneTree | ENSGT00530000063266 | |
| HOGENOM | HOG000013156 | |
| HOVERGEN | HBG051555 | |
| InParanoid | Q14296 | |
| KO | K08290 | |
| OMA | QNPTKVR | |
| OrthoDB | EOG7TBC2C | |
| PhylomeDB | Q14296 | |
| TreeFam | TF331796 | |
| BRENDA | 2.7.11.8 | |
| GeneWiki | FASTK | |
| GenomeRNAi | 10922 | |
| NextBio | 41493 | |
| PRO | PR:Q14296 | |
| Proteomes | UP000005640 | |
| Bgee | Q14296 | |
| CleanEx | HS_FASTK | |
| Genevestigator | Q14296 | |
| GO | GO:0005739 GO:0005524 GO:0033867 GO:0004674 GO:0097190 GO:0006468 GO:0043484 | |
| InterPro | IPR013579 IPR010622 IPR013584 IPR015715 | |
| PANTHER | PTHR21228:SF4 | |
| Pfam | PF06743 PF08368 PF08373 | |
| SMART | SM00952 | |
| PROSITE | PS51286 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0043484 |
regulation of RNA splicing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043484 |
regulation of RNA splicing |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0033867 |
Fas-activated serine/threonine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0097190 |
apoptotic signaling pathway |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Simarro, M et al. (2007) Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. Proc. Natl. Acad. Sci. U.S.A. 104 11370-5 PubMed GONUTS page
- ↑ Izquierdo, JM & Valcárcel, J (2007) Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing. J. Biol. Chem. 282 1539-43 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Tian, Q et al. (1995) Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis. J. Exp. Med. 182 865-74 PubMed GONUTS page
