HUMAN:EAF1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	EAF1
Protein Name(s)	ELL-associated factor 1
External Links
UniProt	Q96JC9
EMBL	AF272973 AK304697 AC027125 BC041329
CCDS	CCDS2626.1
RefSeq	NP_149074.3 XP_005265575.1
UniGene	Hs.716733
ProteinModelPortal	Q96JC9
BioGrid	124514
IntAct	Q96JC9
STRING	9606.ENSP00000380054
PhosphoSite	Q96JC9
DMDM	73919265
MaxQB	Q96JC9
PaxDb	Q96JC9
PRIDE	Q96JC9
Ensembl	ENST00000396842
GeneID	85403
KEGG	hsa:85403
UCSC	uc003bzu.3
CTD	85403
GeneCards	GC03P015468
HGNC	HGNC:20907
HPA	HPA051303
MIM	608315
neXtProt	NX_Q96JC9
PharmGKB	PA134897202
eggNOG	NOG273677
GeneTree	ENSGT00390000017724
HOGENOM	HOG000070137
HOVERGEN	HBG054898
InParanoid	Q96JC9
KO	K15186
OMA	SHQQPYS
PhylomeDB	Q96JC9
TreeFam	TF320864
ChiTaRS	EAF1
GeneWiki	EAF1
GenomeRNAi	85403
NextBio	35477526
PRO	PR:Q96JC9
Proteomes	UP000005640
Bgee	Q96JC9
CleanEx	HS_EAF1
ExpressionAtlas	Q96JC9
Genevestigator	Q96JC9
GO	GO:0015030 GO:0005737 GO:0032783 GO:0016607 GO:0005634 GO:0008023 GO:0006355 GO:0006351
InterPro	IPR027093 IPR019194
PANTHER	PTHR15970
Pfam	PF09816

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0030097	hemopoiesis	PMID:24445282	ECO:0000314			P		Figure 1. Eaf1 promotes hematopoiesis.	complete CACAO 9232
	GO:0010629	negative regulation of gene expression	PMID:24445282	ECO:0000314			P		Figure 3. Eaf1 suppresses human FOXO 3a expression.	complete CACAO 9267
part_of	GO:0008023	transcription elongation factor complex	PMID:22195968	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045171	intercellular bridge	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027093	P		Seeded From UniProt	complete
part_of	GO:0032783	ELL-EAF complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027093	C		Seeded From UniProt	complete
involved_in	GO:0006368	transcription elongation from RNA polymerase II promoter	Reactome:R-HSA-75955 Reactome:R-HSA-112382	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006366	transcription by RNA polymerase II	Reactome:R-HSA-73857	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-113429 Reactome:R-HSA-113414 Reactome:R-HSA-113413 Reactome:R-HSA-113412 Reactome:R-HSA-113411 Reactome:R-HSA-112396 Reactome:R-HSA-112395 Reactome:R-HSA-112392 Reactome:R-HSA-112385 Reactome:R-HSA-112381 Reactome:R-HSA-112379	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0186	C		Seeded From UniProt	complete
part_of	GO:0015030	Cajal body	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0031	C		Seeded From UniProt	complete
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References

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