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HUMAN:DAP1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | DAP (synonyms: DAP1) | |
| Protein Name(s) | Death-associated protein 1
DAP-1 | |
| External Links | ||
| UniProt | P51397 | |
| EMBL | X76105 CR542184 AY266680 BC002726 | |
| CCDS | CCDS3880.1 | |
| PIR | I37274 | |
| RefSeq | NP_001278892.1 NP_004385.1 | |
| UniGene | Hs.75189 | |
| ProteinModelPortal | P51397 | |
| BioGrid | 107981 | |
| IntAct | P51397 | |
| STRING | 9606.ENSP00000230895 | |
| PhosphoSite | P51397 | |
| DMDM | 1706298 | |
| MaxQB | P51397 | |
| PaxDb | P51397 | |
| PeptideAtlas | P51397 | |
| PRIDE | P51397 | |
| DNASU | 1611 | |
| Ensembl | ENST00000230895 | |
| GeneID | 1611 | |
| KEGG | hsa:1611 | |
| UCSC | uc003jez.4 | |
| CTD | 1611 | |
| GeneCards | GC05M010679 | |
| HGNC | HGNC:2672 | |
| MIM | 600954 | |
| neXtProt | NX_P51397 | |
| PharmGKB | PA27140 | |
| eggNOG | NOG84666 | |
| GeneTree | ENSGT00510000049345 | |
| HOGENOM | HOG000039719 | |
| HOVERGEN | HBG005451 | |
| InParanoid | P51397 | |
| OMA | VEKLPHP | |
| OrthoDB | EOG757D0J | |
| PhylomeDB | P51397 | |
| TreeFam | TF329716 | |
| ChiTaRS | DAP | |
| GeneWiki | DAP_(gene) | |
| GenomeRNAi | 1611 | |
| NextBio | 6622 | |
| PRO | PR:P51397 | |
| Proteomes | UP000005640 | |
| Bgee | P51397 | |
| CleanEx | HS_DAP | |
| ExpressionAtlas | P51397 | |
| Genevestigator | P51397 | |
| GO | GO:0070513 GO:0006919 GO:0006915 GO:0097190 GO:0006914 GO:0034198 GO:0010507 GO:0032088 GO:0045892 | |
| InterPro | IPR024130 | |
| PANTHER | PTHR13177 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0097190 |
apoptotic signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0097190 |
apoptotic signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0070513 |
death domain binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034198 |
cellular response to amino acid starvation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010507 |
negative regulation of autophagy |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0097190 |
apoptotic signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000323543 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070513 |
death domain binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000323543 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034198 |
cellular response to amino acid starvation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000323543 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010507 |
negative regulation of autophagy |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000323543 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006914 |
autophagy |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Belokrylov, GA & Zhitnukhin, IuL (1976) [Effect of antibodies to rat and human cerebral cortex and white matter on heterologous T- and B-cells]. Zh. Mikrobiol. Epidemiol. Immunobiol. 66-70 PubMed GONUTS page
- ↑ 2.0 2.1 Deiss, LP et al. (1995) Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 9 15-30 PubMed GONUTS page
- ↑ 3.0 3.1 Koren, I et al. (2010) DAP1, a novel substrate of mTOR, negatively regulates autophagy. Curr. Biol. 20 1093-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
