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HUMAN:ACAD8

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ACAD8 (synonyms: ARC42, IBD)
Protein Name(s) Isobutyryl-CoA dehydrogenase, mitochondrial

Activator-recruited cofactor 42 kDa component ARC42 Acyl-CoA dehydrogenase family member 8 ACAD-8

External Links
UniProt Q9UKU7
EMBL AF126245
AF260689
AF260679
AF260680
AF260681
AF260682
AF260683
AF260684
AF260685
AF260686
AF260687
AF260688
AK000359
AK074640
AK299492
AP000859
CH471065
BC001964
CCDS CCDS8498.1
RefSeq NP_055199.1
UniGene Hs.14791
PDB 1RX0
PDBsum 1RX0
ProteinModelPortal Q9UKU7
SMR Q9UKU7
BioGrid 117965
IntAct Q9UKU7
STRING 9606.ENSP00000281182
DrugBank DB03147
PhosphoSite Q9UKU7
DMDM 26006699
UCD-2DPAGE Q9UKU7
MaxQB Q9UKU7
PaxDb Q9UKU7
PRIDE Q9UKU7
DNASU 27034
Ensembl ENST00000281182
ENST00000374752
GeneID 27034
KEGG hsa:27034
UCSC uc001qhk.3
CTD 27034
GeneCards GC11P134123
HGNC HGNC:87
HPA HPA040689
HPA043903
MIM 604773
611283
neXtProt NX_Q9UKU7
Orphanet 79159
PharmGKB PA24423
eggNOG COG1960
GeneTree ENSGT00760000119007
HOGENOM HOG000131659
HOVERGEN HBG000224
InParanoid Q9UKU7
KO K11538
OMA MTIHNMV
OrthoDB EOG74FF0S
PhylomeDB Q9UKU7
TreeFam TF105052
Reactome REACT_197
UniPathway UPA00362
EvolutionaryTrace Q9UKU7
GeneWiki ACAD8
GenomeRNAi 27034
NextBio 35479818
PRO PR:Q9UKU7
Proteomes UP000005640
Bgee Q9UKU7
CleanEx HS_ACAD8
ExpressionAtlas Q9UKU7
Genevestigator Q9UKU7
GO GO:0005759
GO:0003995
GO:0050660
GO:0009083
GO:0034641
GO:0006629
GO:0006355
GO:0044281
GO:0006351
GO:0006574
Gene3D 1.10.540.10
2.40.110.10
InterPro IPR006089
IPR006091
IPR009075
IPR013786
IPR009100
Pfam PF00441
PF02770
PF02771
SUPFAM SSF47203
SSF56645
PROSITE PS00072

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0003995

acyl-CoA dehydrogenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006089
InterPro:IPR034178

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034178

P

Seeded From UniProt

complete

enables

GO:0016627

oxidoreductase activity, acting on the CH-CH group of donors

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006091
InterPro:IPR009075
InterPro:IPR009100
InterPro:IPR013786
InterPro:IPR036250
InterPro:IPR037069

F

Seeded From UniProt

complete

enables

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013786
InterPro:IPR037069

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006089
InterPro:IPR006091
InterPro:IPR009075
InterPro:IPR009100
InterPro:IPR013786
InterPro:IPR036250
InterPro:IPR037069

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

PMID:10524212[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003995

acyl-CoA dehydrogenase activity

PMID:10524212[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009083

branched-chain amino acid catabolic process

Reactome:R-HSA-70895

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

Reactome:R-HSA-70859

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496
UniProtKB-SubCell:SL-0173

C

Seeded From UniProt

complete

involved_in

GO:0009083

branched-chain amino acid catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0101

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0006574

valine catabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00362

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Telford, EA et al. (1999) Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family. Biochim. Biophys. Acta 1446 371-6 PubMed GONUTS page