HUMAN:A5JSJ9

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	CLDN1 (ECO:0000313 with EMBL:ABQ42705.1)
Protein Name(s)	Claudin (ECO:0000256 with RuleBase:RU060637)
External Links
UniProt	A5JSJ9
EMBL	EF564137 AK312866 CH471052 CH471052
RefSeq	NP_066924.1
UniGene	Hs.439060
SMR	A5JSJ9
DNASU	9076
GeneID	9076
KEGG	hsa:9076
CTD	9076
PharmGKB	PA26557
HOVERGEN	HBG000643
KO	K06087
OMA	IYEGLWM
PhylomeDB	A5JSJ9
ChiTaRS	CLDN1
GenomeRNAi	9076
NextBio	34009
GO	GO:0016324 GO:0005887 GO:0016328 GO:0005923 GO:0005198 GO:0016338 GO:0061436
InterPro	IPR006187 IPR003548 IPR017974 IPR004031
PANTHER	PTHR12002
Pfam	PF00822
PRINTS	PR01077 PR01377
PROSITE	PS01346

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0061436	establishment of skin barrier	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	F		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	C		Seeded From UniProt	complete
involved_in	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	P		Seeded From UniProt	complete
part_of	GO:0016328	lateral plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	C		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	C		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O88551 ensembl:ENSMUSP00000023154	C		Seeded From UniProt	complete
involved_in	GO:1903545	cellular response to butyrate	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:1903348	positive regulation of bicellular tight junction assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0097421	liver regeneration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0090557	establishment of endothelial intestinal barrier	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0071560	cellular response to transforming growth factor beta stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0071548	response to dexamethasone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0071356	cellular response to tumor necrosis factor	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0071346	cellular response to interferon-gamma	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0071284	cellular response to lead ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0070673	response to interleukin-18	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0061772	xenobiotic transport across blood-nerve barrier	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0045471	response to ethanol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0042538	hyperosmotic salinity response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0032496	response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
part_of	GO:0016328	lateral plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	C		Seeded From UniProt	complete
involved_in	GO:0009636	response to toxic substance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0008065	establishment of blood-nerve barrier	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
involved_in	GO:0007568	aging	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	P		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56745 ensembl:ENSRNOP00000002640	C		Seeded From UniProt	complete
enables	GO:0005198	structural molecule activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003548 InterPro:IPR006187	F		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003548 InterPro:IPR006187	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004031	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1003	C		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0796	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000060637	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000060637	C		Seeded From UniProt	complete
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References

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