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HUMAN:3BP2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | SH3BP2 (synonyms: 3BP2) | |
| Protein Name(s) | SH3 domain-binding protein 2
3BP-2 | |
| External Links | ||
| UniProt | P78314 | |
| EMBL | AF000936 U56386 AB000462 AB000463 AK299996 AK312286 AL121750 CH471131 CH471131 CH471131 CH471131 BC022996 | |
| CCDS | CCDS33944.1 CCDS54715.1 CCDS54716.1 | |
| RefSeq | NP_001116153.1 NP_001139327.1 NP_001139328.1 NP_003014.3 XP_005248056.1 | |
| UniGene | Hs.167679 | |
| PDB | 2CR4 3TWR | |
| PDBsum | 2CR4 3TWR | |
| ProteinModelPortal | P78314 | |
| SMR | P78314 | |
| BioGrid | 112350 | |
| IntAct | P78314 | |
| MINT | MINT-254189 | |
| STRING | 9606.ENSP00000348685 | |
| PhosphoSite | P78314 | |
| DMDM | 3023207 | |
| MaxQB | P78314 | |
| PaxDb | P78314 | |
| PRIDE | P78314 | |
| Ensembl | ENST00000356331 ENST00000435136 ENST00000442312 ENST00000452765 ENST00000503393 ENST00000511747 ENST00000513020 ENST00000515737 | |
| GeneID | 6452 | |
| KEGG | hsa:6452 | |
| UCSC | uc003gfi.4 uc011bvp.2 | |
| CTD | 6452 | |
| GeneCards | GC04P002794 | |
| GeneReviews | SH3BP2 | |
| HGNC | HGNC:10825 | |
| HPA | HPA036790 | |
| MIM | 118400 602104 | |
| neXtProt | NX_P78314 | |
| Orphanet | 184 | |
| PharmGKB | PA35733 | |
| eggNOG | NOG42035 | |
| GeneTree | ENSGT00390000002216 | |
| HOVERGEN | HBG000016 | |
| InParanoid | P78314 | |
| KO | K07984 | |
| OMA | SNVFPFK | |
| OrthoDB | EOG7DRJ2X | |
| PhylomeDB | P78314 | |
| SignaLink | P78314 | |
| ChiTaRS | SH3BP2 | |
| EvolutionaryTrace | P78314 | |
| GenomeRNAi | 6452 | |
| NextBio | 25079 | |
| PRO | PR:P78314 | |
| Proteomes | UP000005640 | |
| Bgee | P78314 | |
| CleanEx | HS_SH3BP2 | |
| ExpressionAtlas | P78314 | |
| Genevestigator | P78314 | |
| GO | GO:0005070 GO:0009967 GO:0007165 | |
| Gene3D | 2.30.29.30 3.30.505.10 | |
| InterPro | IPR001849 IPR011993 IPR000980 | |
| Pfam | PF00169 PF00017 | |
| SMART | SM00233 SM00252 | |
| SUPFAM | SSF55550 | |
| PROSITE | PS50003 PS50001 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0048555 |
generative cell nucleus |
PMID:P78314 |
ECO:0000317 |
C |
Fig. 1 shows the structure of the genetic mutation of human SH3BP2 that is found in tumor tissue of a patient with cherubism |
Missing: with/from | ||||
|
enables |
GO:0001784 |
phosphotyrosine residue binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0017124 |
SH3 domain binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1346349 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009967 |
positive regulation of signal transduction |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005070 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009967 |
positive regulation of signal transduction |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005070 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005070 |
SH3/SH2 adaptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005070 |
SH3/SH2 adaptor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0017124 |
SH3 domain binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Mehlitz, A et al. (2010) Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1. J. Cell Biol. 190 143-57 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 Bell, SM et al. (1997) Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 involved in bladder cancer. Genomics 44 163-70 PubMed GONUTS page
