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HHV2H:ICP0

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Species (Taxon ID) Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus2). (10315)
Gene Name(s) RL2
Protein Name(s) E3 ubiquitin-protein ligase ICP0

VMW118 protein

External Links
UniProt P28284
EMBL D10471
Z86099
PIR JQ1501
ProteinModelPortal P28284
Proteomes UP000001874
GO GO:0003677
GO:0016874
GO:0008270
GO:0075342
GO:0039648
GO:0039593
GO:0039548
GO:0006351
Gene3D 3.30.40.10
InterPro IPR018957
IPR001841
IPR013083
IPR017907
Pfam PF00097
SMART SM00184
PROSITE PS00518
PS50089

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0075342

disruption by symbiont of host cell PML body

PMID:20106921[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018957

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0039648

modulation by virus of host protein ubiquitination

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1130
UniProtKB-KW:KW-1128

P

Seeded From UniProt

complete

involved_in

GO:0039503

suppression by virus of host innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1090

P

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0060153

modulation by virus of host cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1121

P

Seeded From UniProt

complete

involved_in

GO:0039593

suppression by virus of host exit from mitosis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1098

P

Seeded From UniProt

complete

involved_in

GO:0039548

suppression by virus of host IRF3 activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1092

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0030683

evasion or tolerance by virus of host immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0899

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Everett, RD et al. (2010) Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins. J. Virol. 84 3476-87 PubMed GONUTS page