HHV11:US9

Species (Taxon ID)	Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1). (10299)
Gene Name(s)	No Information Provided.
Protein Name(s)	Envelope protein US9 10 kDa protein
External Links
UniProt	P06481
EMBL	L00036 X14112 X02138 DQ889502 FJ593289
PIR	A05241
RefSeq	NP_044672.1
GeneID	2703452
Proteomes	UP000009294
GO	GO:0044178 GO:0020002 GO:0044171 GO:0016021 GO:0019031 GO:0019033 GO:0055036 GO:0075733
InterPro	IPR009278
Pfam	PF06072

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0075733	intracellular transport of viral material	PMID:23322573	ECO:0000315			P		In neurotropic strains of the herpes simplex virus (HSV), DNA is transported from the neuron body to the axon terminus. The protein Us9 is involved in the regulation of the genome transport. Figure 2 compares the percentage of transported DNA in cells containing wild type Us9 protein, and two other cells containing different Us9 gene mutations. Figure 2A demonstrates the significant effect the Us9 mutation has on DNA transport on day 3,4, and 5. Figure 2B, a different strain of HSV, demonstrates the significant effect the mutated Us9 protein has on genome transport as well, although the results were only statistically significant for day 3. None the less, the figure demonstrates that Us9 is significantly involved in the transport of the viral genome in neurotropic strains of HSV.	complete CACAO 7875
involved_in	GO:0075733	intracellular transport of virus	PMID:23322573	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0075733	intracellular transport of virus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009278	P		Seeded From UniProt	complete
part_of	GO:0044177	host cell Golgi apparatus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1040	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0946	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0020002	host cell plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1032 UniProtKB-SubCell:SL-0375	C		Seeded From UniProt	complete
part_of	GO:0033644	host cell membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1043	C		Seeded From UniProt	complete
part_of	GO:0019031	viral envelope	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0261	C		Seeded From UniProt	complete
part_of	GO:0044165	host cell endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1038	C		Seeded From UniProt	complete
part_of	GO:0055036	virion membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0275	C		Seeded From UniProt	complete
part_of	GO:0044178	host cell Golgi membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0426	C		Seeded From UniProt	complete
part_of	GO:0044171	host cell smooth endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0445	C		Seeded From UniProt	complete
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