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HADVE:TO1A
Contents
Species (Taxon ID) | Hadronyche versuta (Blue mountains funnel-web spider) (Atraxversutus). (6904) | |
Gene Name(s) | No Information Provided. | |
Protein Name(s) | Omega-hexatoxin-Hv1a
Omega-HXTX-Hv1a Omega-atracotoxin-Hv1a AcTx-Hv1 Omega-AcTx-Hv1a | |
External Links | ||
UniProt | P56207 | |
PDB | 1AXH 1HVW | |
PDBsum | 1AXH 1HVW | |
ProteinModelPortal | P56207 | |
SMR | P56207 | |
ArachnoServer | AS000193 | |
EvolutionaryTrace | P56207 | |
GO | GO:0005576 GO:0019855 GO:0006952 GO:0009405 | |
InterPro | IPR009415 IPR018071 | |
Pfam | PF06357 | |
PROSITE | PS60016 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0019855 |
calcium channel inhibitor activity |
ECO:0000314 |
F |
Fig. 4E "ω-ACTX-Hv1a (open circles)" |
complete | |||||
GO:0019855 |
calcium channel inhibitor activity |
ECO:0000314 |
F |
Fig. 3B "Effect of ω-ACTX-Hv1a on rat HVA calcium channels...extent of current blockage for each channel subtype caused by either 30 μm ω-ACTX-Hv1a" |
complete | |||||
enables |
GO:0019855 |
calcium channel inhibitor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0019855 |
calcium channel inhibitor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006952 |
defense response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0019855 |
calcium channel inhibitor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0090729 |
toxin activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Chong, Y et al. (2007) The omega-atracotoxins: selective blockers of insect M-LVA and HVA calcium channels. Biochem. Pharmacol. 74 623-38 PubMed GONUTS page
- ↑ 2.0 2.1 Tedford, HW et al. (2004) Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels. J. Biol. Chem. 279 44133-40 PubMed GONUTS page