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ECOLI:SBMC

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) sbmC (synonyms: gyrI, yeeB)
Protein Name(s) DNA gyrase inhibitor
External Links
UniProt P33012
EMBL X84885
U00009
U00096
AP009048
PIR H64965
RefSeq NP_416513.1
YP_490251.1
PDB 1JYH
PDBsum 1JYH
ProteinModelPortal P33012
SMR P33012
DIP DIP-9862N
IntAct P33012
MINT MINT-226165
STRING 511145.b2009
PaxDb P33012
PRIDE P33012
EnsemblBacteria AAC75070
BAA15830
GeneID 12931418
946546
KEGG ecj:Y75_p1971
eco:b2009
PATRIC 32119353
EchoBASE EB1838
EcoGene EG11892
eggNOG COG3449
HOGENOM HOG000121896
InParanoid P33012
KO K07470
OMA TPWYQFF
OrthoDB EOG6Z3KJW
BioCyc EcoCyc:EG11892-MONOMER
ECOL316407:JW1991-MONOMER
EvolutionaryTrace P33012
PRO PR:P33012
Proteomes UP000000318
UP000000625
Genevestigator P33012
GO GO:0005737
GO:0008657
GO:0019899
GO:0006974
GO:2000372
GO:2000104
Gene3D 3.20.80.10
HAMAP MF_01896
InterPro IPR010499
IPR024911
IPR029442
IPR011256
Pfam PF06445
SMART SM00871
SUPFAM SSF55136

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008657

DNA topoisomerase (ATP-hydrolyzing) inhibitor activity

PMID:11777918[1]

ECO:0000314

F

Figure 1

complete
CACAO 4866

enables

GO:0008657

DNA topoisomerase (ATP-hydrolyzing) inhibitor activity

PMID:11777918[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

PMID:11967071[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000104

negative regulation of DNA-dependent DNA replication

PMID:9442027[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0019899

enzyme binding

PMID:11777918[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P0AES6

F

Seeded From UniProt

complete

enables

GO:0008657

DNA topoisomerase (ATP-hydrolyzing) inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024911

F

Seeded From UniProt

complete

involved_in

GO:2000372

negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000030794

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000030794

C

Seeded From UniProt

complete

enables

GO:0008657

DNA topoisomerase (ATP-hydrolyzing) inhibitor activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000030794

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Nakanishi, A et al. (2002) Characterization of the interaction between DNA gyrase inhibitor and DNA gyrase of Escherichia coli. J. Biol. Chem. 277 8949-54 PubMed GONUTS page
  2. Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page
  3. Nakanishi, A et al. (1998) Identification of DNA gyrase inhibitor (GyrI) in Escherichia coli. J. Biol. Chem. 273 1933-8 PubMed GONUTS page