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ECOLI:K1PF

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) fruK (synonyms: fpk)
Protein Name(s) 1-phosphofructokinase

Fructose 1-phosphate kinase

External Links
UniProt P0AEW9
EMBL X53948
U00007
U00096
AP009048
PIR B37245
RefSeq NP_416673.1
YP_490407.1
ProteinModelPortal P0AEW9
SMR P0AEW9
IntAct P0AEW9
STRING 511145.b2168
PaxDb P0AEW9
PRIDE P0AEW9
EnsemblBacteria AAC75229
BAA15977
GeneID 12933917
946676
KEGG ecj:Y75_p2130
eco:b2168
PATRIC 32119685
EchoBASE EB0333
EcoGene EG10337
eggNOG COG1105
HOGENOM HOG000265280
InParanoid P0AEW9
KO K00882
OMA GVPKTFY
OrthoDB EOG61KBKF
PhylomeDB P0AEW9
BioCyc EcoCyc:1-PFK-MONOMER
ECOL316407:JW2155-MONOMER
MetaCyc:1-PFK-MONOMER
PRO PR:P0AEW9
Proteomes UP000000318
UP000000625
Genevestigator P0AEW9
GO GO:0008662
GO:0005524
GO:0046835
GO:0006001
Gene3D 3.40.1190.20
InterPro IPR022463
IPR002173
IPR011611
IPR029056
IPR017583
Pfam PF00294
PIRSF PIRSF000535
SUPFAM SSF53613
TIGRFAMs TIGR03168
TIGR03828
PROSITE PS00583
PS00584

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008662

1-phosphofructokinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10337
PANTHER:PTN000062049

F

Seeded From UniProt

complete

enables

GO:0008443

phosphofructokinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10337
EcoGene:EG10700
PANTHER:PTN001317471

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10700
PANTHER:PTN001317471

C

Seeded From UniProt

complete

enables

GO:0008662

1-phosphofructokinase activity

PMID:10833389[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006001

fructose catabolic process

PMID:4579702[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008662

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008662

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008443

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008662

P

Seeded From UniProt

complete

involved_in

GO:0046835

carbohydrate phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008662

P

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017583

P

Seeded From UniProt

complete

enables

GO:0008662

1-phosphofructokinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022463

F

Seeded From UniProt

complete

enables

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002173
InterPro:IPR017583

F

Seeded From UniProt

complete

enables

GO:0008662

1-phosphofructokinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.56

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Veiga-da-Cunha, M et al. (2000) Overexpression and purification of fructose-1-phosphate kinase from Escherichia coli: application to the assay of fructose 1-phosphate. Protein Expr. Purif. 19 48-52 PubMed GONUTS page
  3. Ferenci, T & Kornberg, HL (1973) The utilization of fructose by Escherichia coli. Properties of a mutant defective in fructose 1-phosphate kinase activity. Biochem. J. 132 341-7 PubMed GONUTS page