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ECOLI:ARCB
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | arcB | |
| Protein Name(s) | Aerobic respiration control sensor protein ArcB | |
| External Links | ||
| UniProt | P0AEC3 | |
| EMBL | X53315 U18997 U00096 AP009048 | |
| PIR | D65112 | |
| RefSeq | YP_026207.1 YP_491395.1 | |
| PDB | 1A0B 1BDJ 1FR0 2A0B 2KSD | |
| PDBsum | 1A0B 1BDJ 1FR0 2A0B 2KSD | |
| ProteinModelPortal | P0AEC3 | |
| SMR | P0AEC3 | |
| DIP | DIP-47915N | |
| IntAct | P0AEC3 | |
| MINT | MINT-98513 | |
| STRING | 511145.b3210 | |
| PaxDb | P0AEC3 | |
| PRIDE | P0AEC3 | |
| EnsemblBacteria | AAT48172 BAE77254 | |
| GeneID | 12934428 947887 | |
| KEGG | ecj:Y75_p3130 eco:b3210 | |
| PATRIC | 32121840 | |
| EchoBASE | EB0060 | |
| EcoGene | EG10062 | |
| eggNOG | COG0642 | |
| HOGENOM | HOG000272667 | |
| InParanoid | P0AEC3 | |
| KO | K07648 | |
| OMA | LIEDCIA | |
| OrthoDB | EOG6G4VQG | |
| PhylomeDB | P0AEC3 | |
| BioCyc | EcoCyc:ARCB-MONOMER ECOL316407:JW5536-MONOMER | |
| EvolutionaryTrace | P0AEC3 | |
| PRO | PR:P0AEC3 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AEC3 | |
| GO | GO:0016021 GO:0005886 GO:0005524 GO:0009927 GO:0000155 GO:0000160 GO:0046777 GO:0006355 GO:0023014 GO:0006351 | |
| Gene3D | 1.10.287.130 1.10.287.970 1.20.120.160 3.30.565.10 | |
| InterPro | IPR027460 IPR011006 IPR003661 IPR003594 IPR000014 IPR000700 IPR013767 IPR004358 IPR008207 IPR014409 IPR005467 IPR009082 IPR001789 | |
| Pfam | PF02518 PF00512 PF01627 PF00989 PF00072 | |
| PIRSF | PIRSF003182 | |
| PRINTS | PR00344 | |
| SMART | SM00387 SM00388 SM00073 SM00091 SM00448 | |
| SUPFAM | SSF47226 SSF47384 SSF52172 SSF55785 SSF55874 | |
| TIGRFAMs | TIGR00229 | |
| PROSITE | PS50109 PS50894 PS50113 PS50112 PS50110 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016021 |
integral component of membrane |
ECO:0000314 |
C |
Figure 1: ArcB possesses a cytoplasm-located signal reception site, it is activated only by the membrane-permeating thiol-reductants during aerobiosis, and has two unique cysteine residues in the linker region |
complete | |||||
| GO:0046777 |
protein autophosphorylation |
ECO:0000315 |
P |
Figure 1. shows in vitro autophosphorylation reactions of ArcB |
complete | |||||
| GO:0004673 |
protein histidine kinase activity |
ECO:0000315 |
F |
Figure 2A. shows that the formation of ArcB mutants by substituting leucine to valine across the leucine zipper motif adversely affects both kinase and phosphotase activity in the ArcB protein. |
complete | |||||
|
involved_in |
GO:0046777 |
protein autophosphorylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046777 |
protein autophosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0023014 |
signal transduction by protein phosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009927 |
histidine phosphotransfer kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000155 |
phosphorelay sensor kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0018106 |
peptidyl-histidine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004673 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0018106 |
peptidyl-histidine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004673 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000155 |
phosphorelay sensor kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000160 |
phosphorelay signal transduction system |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001789 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004673 |
protein histidine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004673 |
protein histidine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000160 |
phosphorelay signal transduction system |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Malpica, R et al. (2004) Identification of a quinone-sensitive redox switch in the ArcB sensor kinase. Proc. Natl. Acad. Sci. U.S.A. 101 13318-23 PubMed GONUTS page
- ↑ 2.0 2.1 Peña-Sandoval, GR & Georgellis, D (2010) The ArcB sensor kinase of Escherichia coli autophosphorylates by an intramolecular reaction. J. Bacteriol. 192 1735-9 PubMed GONUTS page
- ↑ Nuñez Oreza, LA et al. (2012) The ArcB leucine zipper domain is required for proper ArcB signaling. PLoS ONE 7 e38187 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Iuchi, S & Lin, EC (1992) Purification and phosphorylation of the Arc regulatory components of Escherichia coli. J. Bacteriol. 174 5617-23 PubMed GONUTS page
- ↑ Iuchi, S et al. (1990) The arcB gene of Escherichia coli encodes a sensor-regulator protein for anaerobic repression of the arc modulon. Mol. Microbiol. 4 715-27 PubMed GONUTS page
- ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page
b
p
- GO:0018106 ! peptidyl-histidine phosphorylation
- GO:0000160 ! phosphorelay signal transduction system
- GO:0000155 ! phosphorelay sensor kinase activity
- GO:0016310 ! phosphorylation
- GO:0005886 ! plasma membrane
- GO:0046777 ! protein autophosphorylation
- GO:0004673 ! protein histidine kinase activity
- Proteobacteria
