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DROME:QVR

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) qvr (synonyms: sss)
Protein Name(s) Protein quiver

Protein sleepless

External Links
UniProt B5A5T4
EMBL EU816195
AE013599
AY089495
RefSeq NP_001137646.1
BioGrid 77570
STRING 7227.FBpp0113067
EnsemblMetazoa FBtr0114575
GeneID 2768718
KEGG dme:Dmel_CG33472
CTD 2768718
FlyBase FBgn0260499
eggNOG NOG74387
InParanoid B5A5T4
OMA MMESSGN
OrthoDB EOG7QC7XG
PhylomeDB B5A5T4
ChiTaRS qvr
GenomeRNAi 2768718
NextBio 848161
Proteomes UP000000803
Bgee B5A5T4
GO GO:0031225
GO:0009897
GO:0005886
GO:0034235
GO:0045837
GO:0045938
GO:0045187
GO:0032222
GO:0030431

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

PMID:18635795[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0009897

external side of plasma membrane

PMID:18635795[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0030431

sleep

PMID:24497543[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0266347

P

Seeded From UniProt

complete

GO:0031225

anchored component of membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0336

C

Seeded From UniProt

complete

GO:0032222

regulation of synaptic transmission, cholinergic

PMID:20010822[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0034235

GPI anchor binding

PMID:18635795[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0045187

regulation of circadian sleep/wake cycle, sleep

PMID:18635795[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0045837

negative regulation of membrane potential

PMID:24497543[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0266347

P

Seeded From UniProt

complete

GO:0045938

positive regulation of circadian sleep/wake cycle, sleep

PMID:18635795[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048511

rhythmic process

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0090

P

Seeded From UniProt

complete

GO:1903049

negative regulation of acetylcholine-gated cation channel activity

PMID:24613312[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0015519

P

Seeded From UniProt

complete

GO:1903049

negative regulation of acetylcholine-gated cation channel activity

PMID:24613312[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0031261

P

Seeded From UniProt

complete

colocalizes_with

GO:0008076

voltage-gated potassium channel complex

PMID:20010822[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Koh, K et al. (2008) Identification of SLEEPLESS, a sleep-promoting factor. Science 321 372-6 PubMed GONUTS page
  2. 2.0 2.1 Shi, M et al. (2014) Identification of Redeye, a new sleep-regulating protein whose expression is modulated by sleep amount. Elife 3 e01473 PubMed GONUTS page
  3. 3.0 3.1 Wu, MN et al. (2010) SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker. Nat. Neurosci. 13 69-75 PubMed GONUTS page
  4. 4.0 4.1 Wu, M et al. (2014) SLEEPLESS is a bifunctional regulator of excitability and cholinergic synaptic transmission. Curr. Biol. 24 621-9 PubMed GONUTS page