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DROME:Q9VB05

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) ALG-2 interacting protein X (ECO:0000313 with EMBL:AAF56740.1)

LD25543p (ECO:0000313 with EMBL:AAL39679.1)

External Links
UniProt Q9VB05
EMBL AE014297
AY069534
RefSeq NP_651582.1
UniGene Dm.7702
MINT MINT-297740
STRING 7227.FBpp0084610
EnsemblMetazoa FBtr0085241
GeneID 43330
KEGG dme:Dmel_CG12876
UCSC CG12876-RA
CTD 43330
FlyBase FBgn0086346
eggNOG KOG2220
ENOG410XQX6
GeneTree ENSGT00780000121909
KO K12200
OMA AYDAYME
OrthoDB EOG091G04NC
GenomeRNAi 43330
Proteomes UP000000803
Bgee FBgn0086346
GO GO:0005813
GO:0070938
GO:0005768
GO:0045171
GO:0030496
GO:0030041
GO:1990182
GO:0048132
GO:0048133
GO:0000281
GO:0046330
GO:0043162
Gene3D 1.25.40.280
InterPro IPR025304
IPR004328
Pfam PF13949
PF03097
SMART SM01041
PROSITE PS51180

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000281

mitotic cytokinesis

PMID:25635693[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0005515

protein binding

PMID:16698022[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9NHP2

F

Seeded From UniProt

GO:0005768

endosome

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

SGD:S000006005

C

Seeded From UniProt

GO:0005813

centrosome

PMID:25635693[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0030041

actin filament polymerization

PMID:12975351[3]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0030496

midbody

PMID:25635693[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0043162

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

SGD:S000006005

P

Seeded From UniProt

GO:0045171

intercellular bridge

PMID:25635693[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0046330

positive regulation of JNK cascade

PMID:16698022[2]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0048132

female germ-line stem cell asymmetric division

PMID:25635693[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0048133

male germ-line stem cell asymmetric division

PMID:25635693[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0070938

contractile ring

PMID:25635693[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:1990182

exosomal secretion

PMID:25154396[4]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

contributes_to

GO:0004843

thiol-dependent ubiquitin-specific protease activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

SGD:S000006005

F

Seeded From UniProt

GO:0005813

centrosome

PMID:25635693[1]

IDA: Inferred from Direct Assay

C

Organism: Drosophilia fruit fly Protein: ALIX Figure 1. (B-E) ALIX localizes at centrosomes in (B) metaphase, (C) early anaphase, (D) late anaphase and (E) early telophase

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Eikenes, ÅH et al. (2015) ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo. PLoS Genet. 11 e1004904 PubMed GONUTS page
  2. 2.0 2.1 Tsuda, M et al. (2006) POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila. FEBS Lett. 580 3296-300 PubMed GONUTS page
  3. Rogers, SL et al. (2003) Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J. Cell Biol. 162 1079-88 PubMed GONUTS page
  4. Corrigan, L et al. (2014) BMP-regulated exosomes from Drosophila male reproductive glands reprogram female behavior. J. Cell Biol. 206 671-88 PubMed GONUTS page