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DROME:Q9V3N4
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Huntingtin (ECO:0000313 with EMBL:AAF56808.1)
Huntington disease protein homolog (ECO:0000313 with EMBL:AAF03255.1) | |
| External Links | ||
| UniProt | Q9V3N4 | |
| EMBL | AF146362 AF147779 AE014297 | |
| RefSeq | NP_001263041.1 NP_651629.1 | |
| UniGene | Dm.1357 | |
| EnsemblMetazoa | FBtr0085310 | |
| GeneID | 43392 | |
| KEGG | dme:Dmel_CG9995 | |
| UCSC | CG9995-RA | |
| CTD | 3064 | |
| FlyBase | FBgn0027655 | |
| GeneTree | ENSGT00390000015863 | |
| KO | K04533 | |
| OMA | KFCEICE | |
| PhylomeDB | Q9V3N4 | |
| ChiTaRS | htt | |
| GenomeRNAi | 43392 | |
| NextBio | 833691 | |
| Proteomes | UP000000803 | |
| GO | GO:0005737 GO:0008088 GO:0000132 GO:0048812 GO:0048489 | |
| Gene3D | 1.25.10.10 | |
| InterPro | IPR011989 IPR016024 IPR028426 IPR024613 | |
| PANTHER | PTHR10170 | |
| Pfam | PF12372 | |
| SUPFAM | SSF48371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0048489 |
synaptic vesicle transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008088 |
axo-dendritic transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000132 |
establishment of mitotic spindle orientation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0033697 |
positive regulation of extent of heterochromatin assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043005 |
neuron projection |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008088 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045202 |
synapse |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0048489 |
C |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Power, D et al. (2012) In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin. Neuroreport 23 970-7 PubMed GONUTS page
- ↑ Zala, D et al. (2013) Huntingtin's function in axonal transport is conserved in Drosophila melanogaster. PLoS ONE 8 e60162 PubMed GONUTS page
- ↑ Godin, JD et al. (2010) Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron 67 392-406 PubMed GONUTS page
- ↑ Zhang, S et al. () Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Dis Model Mech 2 247-66 PubMed GONUTS page
- ↑ Dietz, KN et al. (2015) The Drosophila Huntington's disease gene ortholog dhtt influences chromatin regulation during development. Hum. Mol. Genet. 24 330-45 PubMed GONUTS page
