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DROME:Q9V3N4

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) Huntingtin (ECO:0000313 with EMBL:AAF56808.1)

Huntington disease protein homolog (ECO:0000313 with EMBL:AAF03255.1)

External Links
UniProt Q9V3N4
EMBL AF146362
AF147779
AE014297
RefSeq NP_001263041.1
NP_651629.1
UniGene Dm.1357
EnsemblMetazoa FBtr0085310
GeneID 43392
KEGG dme:Dmel_CG9995
UCSC CG9995-RA
CTD 3064
FlyBase FBgn0027655
GeneTree ENSGT00390000015863
KO K04533
OMA KFCEICE
PhylomeDB Q9V3N4
ChiTaRS htt
GenomeRNAi 43392
NextBio 833691
Proteomes UP000000803
GO GO:0005737
GO:0008088
GO:0000132
GO:0048812
GO:0048489
Gene3D 1.25.10.10
InterPro IPR011989
IPR016024
IPR028426
IPR024613
PANTHER PTHR10170
Pfam PF12372
SUPFAM SSF48371

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000132

establishment of mitotic spindle orientation

PMID:20696378[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:19380309[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0008088

axon cargo transport

PMID:23555909[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048489

synaptic vesicle transport

PMID:23032403[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048812

neuron projection morphogenesis

PMID:18604272[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Godin, JD et al. (2010) Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron 67 392-406 PubMed GONUTS page
  2. Zhang, S et al. () Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Dis Model Mech 2 247-66 PubMed GONUTS page
  3. Zala, D et al. (2013) Huntingtin's function in axonal transport is conserved in Drosophila melanogaster. PLoS ONE 8 e60162 PubMed GONUTS page
  4. Power, D et al. (2012) In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin. Neuroreport 23 970-7 PubMed GONUTS page
  5. Sepp, KJ et al. (2008) Identification of neural outgrowth genes using genome-wide RNAi. PLoS Genet. 4 e1000111 PubMed GONUTS page