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DROME:Q7YU85

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) cindr (ECO:0000313 with FlyBase:FBgn0027598) (synonyms: BcDNA:GH03163 (ECO:0000313 with EMBL:AAQ22404.1))
Protein Name(s) SD08724p (ECO:0000313 with EMBL:AAQ22404.1)
External Links
UniProt Q7YU85
EMBL BT009935
ProteinModelPortal Q7YU85
IntAct Q7YU85
MINT MINT-7965375
STRING 7227.FBpp0302572
PaxDb Q7YU85
PeptideAtlas Q7YU85
PRIDE Q7YU85
FlyBase FBgn0027598
eggNOG KOG4348
ENOG410XQBY
OrthoDB EOG091G08MZ
Reactome [www.reactome.org/content/detail/R-DME-182971 R-DME-182971]
[www.reactome.org/content/detail/R-DME-6807004 R-DME-6807004]
[www.reactome.org/content/detail/R-DME-8856825 R-DME-8856825]
[www.reactome.org/content/detail/R-DME-8856828 R-DME-8856828]
SignaLink Q7YU85
ChiTaRS cindr
Bgee FBgn0027598
GO GO:0032154
GO:0045171
GO:0030496
GO:0050839
GO:0017124
GO:0007015
GO:0007298
GO:0048749
GO:0001745
GO:0043063
GO:0046331
GO:0048260
GO:0032465
InterPro IPR001452
Pfam PF00018
PF14604
SMART SM00326
SUPFAM SSF50044
PROSITE PS50002

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001745

compound eye morphogenesis

PMID:18362180[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0007015

actin filament organization

PMID:18362180[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0007298

border follicle cell migration

PMID:20385776[2]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0017124

SH3 domain binding

PMID:20385776[2]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0030496

midbody

PMID:20451383[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0032154

cleavage furrow

PMID:20451383[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0032465

regulation of cytokinesis

PMID:20451383[3]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0043063

intercellular bridge organization

PMID:20451383[3]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0045171

intercellular bridge

PMID:20451383[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0046331

lateral inhibition

PMID:19363474[4]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0048260

positive regulation of receptor-mediated endocytosis

PMID:20385776[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0053558

P

Seeded From UniProt

GO:0048749

compound eye development

PMID:19753121[5]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0050839

cell adhesion molecule binding

PMID:23027549[6]

IPI: Inferred from Physical Interaction

FB:FBgn0003285

F

Seeded From UniProt

GO:0050839

cell adhesion molecule binding

PMID:23027549[6]

IPI: Inferred from Physical Interaction

FB:FBgn0029082

F

Seeded From UniProt

GO:0045169

fusome

PMID:23499247[7]

IDA: Inferred from Direct Assay

C

Organism: Drosophila male Protein: Q7YU85 cindr Figure 3. B, C. Cindr translocates to the fusome of maturing primary spermatocytes. n. (B) Magnification of the area indicated in (A) shows a weak band of Cindr. (C)–(C00) Immunostaining wild-type males for Cindr (green) and Phalloidin to visualize F-actin (red) reveals a band of Cindr co-localizing with the fusome (arrows) during the primary spermatocyte growth phase between the ring canals, highlighted by arrows, and indicates translocation to the fusome

complete
CACAO 12341

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Johnson, RI et al. (2008) The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. J. Cell Biol. 180 1191-204 PubMed GONUTS page
  2. 2.0 2.1 2.2 Quinones, GA et al. (2010) I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration. J. Cell Biol. 189 353-67 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Haglund, K et al. (2010) Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster. Curr. Biol. 20 944-50 PubMed GONUTS page
  4. Mummery-Widmer, JL et al. (2009) Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature 458 987-92 PubMed GONUTS page
  5. Johnson, RI & Cagan, RL (2009) A quantitative method to analyze Drosophila pupal eye patterning. PLoS ONE 4 e7008 PubMed GONUTS page
  6. 6.0 6.1 Johnson, RI et al. (2012) Interactions between Drosophila IgCAM adhesion receptors and cindr, the Cd2ap/Cin85 ortholog. Dev. Dyn. 241 1933-43 PubMed GONUTS page
  7. Eikenes, ÅH et al. (2013) Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline. Dev. Biol. 377 9-20 PubMed GONUTS page