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DROME:Q7YU85
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | cindr (ECO:0000313 with FlyBase:FBgn0027598) (synonyms: BcDNA:GH03163 (ECO:0000313 with EMBL:AAQ22404.1)) | |
| Protein Name(s) | SD08724p (ECO:0000313 with EMBL:AAQ22404.1) | |
| External Links | ||
| UniProt | Q7YU85 | |
| EMBL | BT009935 | |
| ProteinModelPortal | Q7YU85 | |
| IntAct | Q7YU85 | |
| MINT | MINT-7965375 | |
| STRING | 7227.FBpp0302572 | |
| PaxDb | Q7YU85 | |
| PeptideAtlas | Q7YU85 | |
| PRIDE | Q7YU85 | |
| FlyBase | FBgn0027598 | |
| eggNOG | KOG4348 ENOG410XQBY | |
| OrthoDB | EOG091G08MZ | |
| Reactome | [www.reactome.org/content/detail/R-DME-182971 R-DME-182971] [www.reactome.org/content/detail/R-DME-6807004 R-DME-6807004] [www.reactome.org/content/detail/R-DME-8856825 R-DME-8856825] [www.reactome.org/content/detail/R-DME-8856828 R-DME-8856828] | |
| SignaLink | Q7YU85 | |
| ChiTaRS | cindr | |
| Bgee | FBgn0027598 | |
| GO | GO:0032154 GO:0045171 GO:0030496 GO:0050839 GO:0017124 GO:0007015 GO:0007298 GO:0048749 GO:0001745 GO:0043063 GO:0046331 GO:0048260 GO:0032465 | |
| InterPro | IPR001452 | |
| Pfam | PF00018 PF14604 | |
| SMART | SM00326 | |
| SUPFAM | SSF50044 | |
| PROSITE | PS50002 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0043063 |
intercellular bridge organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0045169 |
fusome |
ECO:0000314 |
C |
Organism: Drosophila male Protein: Q7YU85 cindr Figure 3. B, C. Cindr translocates to the fusome of maturing primary spermatocytes. n. (B) Magnification of the area indicated in (A) shows a weak band of Cindr. (C)–(C00) Immunostaining wild-type males for Cindr (green) and Phalloidin to visualize F-actin (red) reveals a band of Cindr co-localizing with the fusome (arrows) during the primary spermatocyte growth phase between the ring canals, highlighted by arrows, and indicates translocation to the fusome |
complete | |||||
|
part_of |
GO:0045171 |
intercellular bridge |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032154 |
cleavage furrow |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030496 |
midbody |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032465 |
regulation of cytokinesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0017124 |
SH3 domain binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048260 |
positive regulation of receptor-mediated endocytosis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0053558 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007298 |
border follicle cell migration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048749 |
compound eye development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007015 |
actin filament organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001745 |
compound eye morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050839 |
cell adhesion molecule binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0029082 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050839 |
cell adhesion molecule binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0003285 |
F |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Haglund, K et al. (2010) Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster. Curr. Biol. 20 944-50 PubMed GONUTS page
- ↑ Eikenes, ÅH et al. (2013) Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline. Dev. Biol. 377 9-20 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Quinones, GA et al. (2010) I-BAR protein antagonism of endocytosis mediates directional sensing during guided cell migration. J. Cell Biol. 189 353-67 PubMed GONUTS page
- ↑ Johnson, RI & Cagan, RL (2009) A quantitative method to analyze Drosophila pupal eye patterning. PLoS ONE 4 e7008 PubMed GONUTS page
- ↑ 5.0 5.1 Johnson, RI et al. (2008) The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. J. Cell Biol. 180 1191-204 PubMed GONUTS page
- ↑ 6.0 6.1 Johnson, RI et al. (2012) Interactions between Drosophila IgCAM adhesion receptors and cindr, the Cd2ap/Cin85 ortholog. Dev. Dyn. 241 1933-43 PubMed GONUTS page
