GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
DROME:CO4A1
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | Cg25C (synonyms: DCg1) | |
| Protein Name(s) | Collagen alpha-1(IV) chain | |
| External Links | ||
| UniProt | P08120 | |
| EMBL | J02727 M23704 M96575 AE014134 AE014134 AE014134 V00200 M28334 | |
| PIR | A31893 | |
| RefSeq | NP_723044.1 NP_723045.1 NP_723046.1 | |
| UniGene | Dm.5178 | |
| ProteinModelPortal | P08120 | |
| SMR | P08120 | |
| BioGrid | 59908 | |
| DIP | DIP-59819N | |
| IntAct | P08120 | |
| MINT | MINT-1738460 | |
| STRING | 7227.FBpp0078641 | |
| PaxDb | P08120 | |
| PRIDE | P08120 | |
| EnsemblMetazoa | FBtr0079001 FBtr0079002 FBtr0079003 | |
| GeneID | 33727 | |
| KEGG | dme:Dmel_CG4145 | |
| CTD | 33727 | |
| FlyBase | FBgn0000299 | |
| eggNOG | NOG12793 | |
| GeneTree | ENSGT00770000120455 | |
| InParanoid | P08120 | |
| KO | K06237 | |
| OMA | PACASET | |
| OrthoDB | EOG7RZ5P3 | |
| PhylomeDB | P08120 | |
| Reactome | REACT_180755 REACT_215998 | |
| ChiTaRS | Cg25C | |
| GenomeRNAi | 33727 | |
| NextBio | 784979 | |
| PRO | PR:P08120 | |
| Proteomes | UP000000803 | |
| Bgee | P08120 | |
| ExpressionAtlas | P08120 | |
| GO | GO:0005587 GO:0005201 GO:0007391 GO:0035848 | |
| Gene3D | 2.170.240.10 | |
| InterPro | IPR016187 IPR008160 IPR001442 | |
| Pfam | PF01413 PF01391 | |
| SMART | SM00111 | |
| SUPFAM | SSF56436 | |
| PROSITE | PS51403 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0031012 |
extracellular matrix |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88445 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030198 |
extracellular matrix organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1095415 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88452 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005604 |
basement membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000299 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005201 |
extracellular matrix structural constituent |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104687 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060729 |
intestinal epithelial structure maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048621 |
post-embryonic digestive tract morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055013 |
cardiac muscle cell development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035848 |
oviduct morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005587 |
collagen type IV trimer |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005587 |
collagen type IV trimer |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005587 |
collagen type IV trimer |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005604 |
basement membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071711 |
basement membrane organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005604 |
basement membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005201 |
extracellular matrix structural constituent |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005581 |
collagen trimer |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007391 |
dorsal closure |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005587 |
collagen type IV trimer |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005604 |
basement membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005581 |
collagen trimer |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 Kiss, M et al. (2016) Drosophila type IV collagen mutation associates with immune system activation and intestinal dysfunction. Matrix Biol. 49 120-131 PubMed GONUTS page
- ↑ Hollfelder, D et al. (2014) Distinct functions of the laminin β LN domain and collagen IV during cardiac extracellular matrix formation and stabilization of alary muscle attachments revealed by EMS mutagenesis in Drosophila. BMC Dev. Biol. 14 26 PubMed GONUTS page
- ↑ Kelemen-Valkony, I et al. (2012) Drosophila basement membrane collagen col4a1 mutations cause severe myopathy. Matrix Biol. 31 29-37 PubMed GONUTS page
- ↑ Hynes, RO & Zhao, Q (2000) The evolution of cell adhesion. J. Cell Biol. 150 F89-96 PubMed GONUTS page
- ↑ 6.0 6.1 Noselli, S & Agnès, F (1999) Roles of the JNK signaling pathway in Drosophila morphogenesis. Curr. Opin. Genet. Dev. 9 466-72 PubMed GONUTS page
- ↑ Le Parco, Y et al. (1986) Characterization and expression of collagen-like genes in Drosophila melanogaster. Biol. Cell 56 217-26 PubMed GONUTS page
- ↑ Isabella, AJ & Horne-Badovinac, S (2016) Rab10-Mediated Secretion Synergizes with Tissue Movement to Build a Polarized Basement Membrane Architecture for Organ Morphogenesis. Dev. Cell 38 47-60 PubMed GONUTS page
- ↑ Dai, J et al. (2018) Dissection of Nidogen function in Drosophila reveals tissue-specific mechanisms of basement membrane assembly. PLoS Genet. 14 e1007483 PubMed GONUTS page
- ↑ Denef, N et al. (2008) Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. Dev. Cell 14 354-64 PubMed GONUTS page
- ↑ Fessler, LI et al. (1994) Drosophila extracellular matrix. Meth. Enzymol. 245 271-94 PubMed GONUTS page
c
e
h
n
