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DROME:CCAP

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) CCAP (ECO:0000312 with EMBL:AAF56045.1)
Protein Name(s) Cardioactive peptide

Cardioacceleratory peptide 2a Crustacean cardioactive peptide CCAP

External Links
UniProt Q9VCW0
EMBL AE014297
RefSeq NP_001262846.1
NP_651083.2
UniGene Dm.31330
PDB 1Y49
PDBsum 1Y49
BioGrid 67633
IntAct Q9VCW0
MINT MINT-319409
PaxDb Q9VCW0
PRIDE Q9VCW0
GeneID 42683
KEGG dme:Dmel_CG4910
CTD 42683
FlyBase FBgn0039007
eggNOG NOG114437
InParanoid Q9VCW0
OrthoDB EOG7V4B19
EvolutionaryTrace Q9VCW0
GenomeRNAi 42683
NextBio 830042
Proteomes UP000000803
Bgee Q9VCW0
GO GO:0005615
GO:0005184
GO:0071855
GO:0007218
GO:0010460
InterPro IPR024276
Pfam PF11105
ProDom PD171284

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005179

hormone activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

GO:0005184

neuropeptide hormone activity

PMID:11179818[1]

ISS: Inferred from Sequence or Structural Similarity

F

Seeded From UniProt

Missing: with/from

GO:0005184

neuropeptide hormone activity

PMID:11381038[2]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

GO:0005615

extracellular space

PMID:15898062[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0007218

neuropeptide signaling pathway

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0527

P

Seeded From UniProt

complete

GO:0007218

neuropeptide signaling pathway

PMID:11179818[1]

ISS: Inferred from Sequence or Structural Similarity

P

Seeded From UniProt

Missing: with/from

GO:0007218

neuropeptide signaling pathway

PMID:12646179[4]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0010460

positive regulation of heart rate

PMID:15898062[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0071855

neuropeptide receptor binding

PMID:12177421[5]

IPI: Inferred from Physical Interaction

FB:FBgn0039396

F

Seeded From UniProt

complete

GO:0071855

neuropeptide receptor binding

PMID:12646179[4]

IPI: Inferred from Physical Interaction

FB:FBgn0039396

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Vanden Broeck, J (2001) Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster. Peptides 22 241-54 PubMed GONUTS page
  2. Hewes, RS & Taghert, PH (2001) Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome. Genome Res. 11 1126-42 PubMed GONUTS page
  3. 3.0 3.1 Dulcis, D et al. (2005) Role of the neuropeptide CCAP in Drosophila cardiac function. J. Neurobiol. 64 259-74 PubMed GONUTS page
  4. 4.0 4.1 Cazzamali, G et al. (2003) Molecular identification of a Drosophila G protein-coupled receptor specific for crustacean cardioactive peptide. Biochem. Biophys. Res. Commun. 303 146-52 PubMed GONUTS page
  5. Park, Y et al. (2002) Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand-receptor coevolution. Proc. Natl. Acad. Sci. U.S.A. 99 11423-8 PubMed GONUTS page