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DROME:BURS
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | Burs (ECO:0000312 with FlyBase:FBgn0038901) (synonyms: burs-alpha) | |
| Protein Name(s) | Bursicon
Bursicon subunit alpha Cuticle-tanning hormone | |
| External Links | ||
| UniProt | Q9VD83 | |
| EMBL | AY672905 AY672906 AJ862523 AM294583 AM294584 AM294585 AM294586 AM294587 AM294588 AM294589 AM294590 AM294591 AM294592 AM294593 AM294594 AE014297 | |
| RefSeq | NP_650983.1 | |
| UniGene | Dm.25481 | |
| ProteinModelPortal | Q9VD83 | |
| SMR | Q9VD83 | |
| PRIDE | Q9VD83 | |
| EnsemblMetazoa | FBtr0084131 | |
| GeneID | 42560 | |
| KEGG | dme:Dmel_CG13419 | |
| CTD | 42560 | |
| FlyBase | FBgn0038901 | |
| eggNOG | NOG320464 | |
| InParanoid | Q9VD83 | |
| OMA | DEGPLNN | |
| OrthoDB | EOG79KPGZ | |
| PhylomeDB | Q9VD83 | |
| GenomeRNAi | 42560 | |
| NextBio | 829426 | |
| Proteomes | UP000000803 | |
| Bgee | Q9VD83 | |
| ExpressionAtlas | Q9VD83 | |
| GO | GO:0031395 GO:0005576 GO:0043195 GO:0005179 GO:0046982 GO:0007593 GO:0048067 | |
| InterPro | IPR006207 IPR004133 | |
| Pfam | PF03045 | |
| PROSITE | PS01225 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0048067 |
cuticle pigmentation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046982 |
protein heterodimerization activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007593 |
chitin-based cuticle sclerotization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005179 |
hormone activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030709 |
border follicle cell delamination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007298 |
border follicle cell migration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0036335 |
intestinal stem cell homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043195 |
terminal bouton |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031395 |
bursicon neuropeptide hormone complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000305 |
curator inference used in manual assertion |
GO:0031395 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031395 |
bursicon neuropeptide hormone complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0264810 |
C |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0071855 |
neuropeptide receptor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0003255 |
F |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005179 |
hormone activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Dewey, EM et al. (2004) Identification of the gene encoding bursicon, an insect neuropeptide responsible for cuticle sclerotization and wing spreading. Curr. Biol. 14 1208-13 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Mendive, FM et al. (2005) Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2. FEBS Lett. 579 2171-6 PubMed GONUTS page
- ↑ 3.0 3.1 Anllo, L & Schüpbach, T (2016) Signaling through the G-protein-coupled receptor Rickets is important for polarity, detachment, and migration of the border cells in Drosophila. Dev. Biol. 414 193-206 PubMed GONUTS page
- ↑ Scopelliti, A et al. (2014) Local control of intestinal stem cell homeostasis by enteroendocrine cells in the adult Drosophila midgut. Curr. Biol. 24 1199-211 PubMed GONUTS page
- ↑ Loveall, BJ & Deitcher, DL (2010) The essential role of bursicon during Drosophila development. BMC Dev. Biol. 10 92 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Luo, CW et al. (2005) Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proc. Natl. Acad. Sci. U.S.A. 102 2820-5 PubMed GONUTS page
