DICDI:CPNA

Species (Taxon ID)	Dictyostelium discoideum (Slime mold). (44689)
Gene Name(s)	cpnA
Protein Name(s)	Copine-A
External Links
UniProt	Q7YXU4
EMBL	AY332759 AAFI02000199
RefSeq	XP_629291.1
ProteinModelPortal	Q7YXU4
STRING	44689.DDB_0215368
EnsemblProtists	DDB0215368
GeneID	8629014
KEGG	ddi:DDB_G0293008
dictyBase	DDB_G0293008
eggNOG	NOG269302
InParanoid	Q7YXU4
OMA	TEMIKDS
PhylomeDB	Q7YXU4
Proteomes	UP000002195 UP000002195
GO	GO:0005829 GO:0016020 GO:0005544 GO:0005215 GO:0031154 GO:0006971 GO:0006629 GO:0000281 GO:0046956 GO:0031157 GO:0060359 GO:0051592 GO:0031149 GO:0040040 GO:0043052 GO:0016192
Gene3D	2.60.40.150
InterPro	IPR000008 IPR010734 IPR002035
Pfam	PF00168 PF07002
SMART	SM00239 SM00327
SUPFAM	SSF49562 SSF53300
PROSITE	PS50004

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
acts_upstream_of_or_within	GO:0060359	response to ammonium ion	PMID:21950343^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051592	response to calcium ion	PMID:20525180^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046956	positive phototaxis	PMID:21950343^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043052	thermotaxis	PMID:21950343^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
colocalizes_with	GO:0031902	late endosome membrane	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
colocalizes_with	GO:0031901	early endosome membrane	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
colocalizes_with	GO:0031164	contractile vacuolar membrane	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031157	regulation of aggregate size involved in sorocarp development	PMID:20525180^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031154	culmination involved in sorocarp development	PMID:20525180^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031154	culmination involved in sorocarp development	PMID:17259548^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031149	sorocarp stalk cell differentiation	PMID:20525180^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
colocalizes_with	GO:0030670	phagocytic vesicle membrane	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006971	hypotonic response	PMID:17259548^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
colocalizes_with	GO:0005886	plasma membrane	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	PMID:16343335^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000281	mitotic cytokinesis	PMID:17259548^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0071277	cellular response to calcium ion	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1334445 MGI:MGI:2387578 PANTHER:PTN000091987 UniProtKB:O75131 UniProtKB:Q99829 UniProtKB:Q9UBL6	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1334445 MGI:MGI:2387578 PANTHER:PTN000091987 TAIR:locus:2036074 TAIR:locus:2156186 TAIR:locus:2183299 UniProtKB:O75131 UniProtKB:Q9UBL6 WB:WBGene00012128 dictyBase:DDB_G0293008	C	Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000091987 TAIR:locus:2156186 UniProtKB:O75131 dictyBase:DDB_G0293008	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Flegel, KA et al. (2011) Copine A is expressed in prestalk cells and regulates slug phototaxis and thermotaxis in developing Dictyostelium. Dev. Growth Differ. 53 948-59 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Smith, TS et al. (2010) Copine A plays a role in the differentiation of stalk cells and the initiation of culmination in Dictyostelium development. BMC Dev. Biol. 10 59 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Damer, CK et al. (2005) Copine A, a calcium-dependent membrane-binding protein, transiently localizes to the plasma membrane and intracellular vacuoles in Dictyostelium. BMC Cell Biol. 6 46 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Damer, CK et al. (2007) Copine A is required for cytokinesis, contractile vacuole function, and development in Dictyostelium. Eukaryotic Cell 6 430-42 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21950343-1] 1.0 ^1.1 ^1.2 Flegel, KA et al. (2011) Copine A is expressed in prestalk cells and regulates slug phototaxis and thermotaxis in developing Dictyostelium. Dev. Growth Differ. 53 948-59 PubMed GONUTS page

[PMID:20525180-2] 2.0 ^2.1 ^2.2 ^2.3 Smith, TS et al. (2010) Copine A plays a role in the differentiation of stalk cells and the initiation of culmination in Dictyostelium development. BMC Dev. Biol. 10 59 PubMed GONUTS page

[PMID:16343335-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Damer, CK et al. (2005) Copine A, a calcium-dependent membrane-binding protein, transiently localizes to the plasma membrane and intracellular vacuoles in Dictyostelium. BMC Cell Biol. 6 46 PubMed GONUTS page

[PMID:17259548-4] 4.0 ^4.1 ^4.2 Damer, CK et al. (2007) Copine A is required for cytokinesis, contractile vacuole function, and development in Dictyostelium. Eukaryotic Cell 6 430-42 PubMed GONUTS page

[PMID:21873635-5] 5.0 ^5.1 ^5.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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DICDI:CPNA

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