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Category:Team Voldemort

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorPSEAI:A0A069QIQ9Seannash, Team Voldemort2017-04-09 15:34:45 CDTGO:0009405 pathogenesis (P)PMID:24491574ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 1. A. Pseudomonas aeruginosa (STRAIN: PAK) PrtR mutant showed lower CFU in mice lungs compared to wild-type when the mice were intranasally inoculated.

challenge
updatedbyinstructorPSEAI:Q9RLJ1Madisonmarion, Team Voldemort2017-04-07 11:24:24 CDTGO:0009405 pathogenesis (P)PMID:22666466ECO:0000316 genetic interaction evidence used in manual assertion

Pseudomonas aeruginosa (PA01 Strain) czcR

"Figure 4 CzcR is required for the full virulence of P. aeruginosa."

" In our assay, an infection with the wild type strain killed 50% of the population within circa 3 days of contact with bacteria and all worms were dead after 4 days (Fig. 4). In contrast, the virulence of the ΔczcRS mutant was significantly reduced since 50% of the worms were still alive after 5 days of contact. The virulence of the ΔczcRS mutant strain complemented with czcR on the pRWT plasmid was partially restored since 50% of the worms were dead after 4 days and less than 20% of the worm population was alive after 5 days, while no complementation was observed with the czcS gene (Fig. 4).

challenge
acceptableECOLX:A0A0K4BFT8Seannash, Team Voldemort2017-04-05 11:33:44 CDTGO:0009405 pathogenesis (P)PMID:23958403ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 2. Avian Pathogenic Escherichia coli (STRAIN: 078: K80:H9) luxS (an S-ribosylhomocysteine lyase) mutant showed reduced chicken embryo lethality compared to wild-type and luxS/p-luxS carrying pSM8 inoculated in embryonated chicken eggs.

challenge
updatedbyinstructorECOK1:A0A0H2Z3A5Madisonmarion, Team Voldemort2017-04-05 11:31:20 CDTGO:0044650 adhesion of symbiont to host cell (P)PMID:25487442ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 3. Quantification of the adhesion of Avian Pathogenic Escherichia coli (Strain: SCI-07 strain) nirC (major nitrite transporter) mutant, complemented or wild-type strains showed lower initial mortality rate; indicative of delayed or decreased pathogenicity.

challenge
unacceptableECOLX:E2QFM3Steffanstroh, Team Voldemort2017-04-05 11:06:13 CDTGO:0009405 pathogenesis (P)PMID:25487442ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. S2. Survival rate of one-day-old chickens challenged with either Avian Pathogenic Escherichia coli (Strain: SCI-07 strain) nirC (major nitrite transporter) mutant, complemented or wild-type strains showed lower initial mortality rate; indicative of delayed or decreased pathogenicity.

challenge
acceptableECOLX:IUCASteffanstroh, Team Voldemort2017-04-03 11:45:03 CDTGO:0009405 pathogenesis (P)PMID:23460907ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5. Colonization and persistence of wild-type strain Escherichia coli E058 and its mutant E058∆ iucA. The ability of E058 ∆iucA to colonize was significantly less than the wild-type in tissue samples from an individual chicken

challenge
acceptableECOLX:A0A0E1L6G7Madisonmarion, Team Voldemort2017-03-26 09:33:02 CDTGO:0009405 pathogenesis (P)PMID:26965678ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 5

Survival assay. One-day-old broiler chicks showed higher survival rates when infected with Escherichia coli (SEPT362) mutant ∆ychO compared to the E.coli (SEPT362) WT strain

challenge
acceptableECOLX:E2QL90Cherylrood, Team Voldemort2017-03-25 23:54:29 CDTGO:0009405 pathogenesis (P)PMID:25768126ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 3 Survival assay showed that

seven-day-old ducks inoculated with Escherichia coli (DE205B) had lower survival rates than ducks inoculated with E. coli (DE205B) ΔibeR mutant

challenge
acceptableECOLX:A0A085PA38Cherylrood, Team Voldemort2017-03-25 23:50:21 CDTGO:0009405 pathogenesis (P)PMID:23504015ECO:0000315 mutant phenotype evidence used in manual assertion

Table 3. 100% Death in WT avian Escherichia coli (serotype O2 APEC E058) compared to 0% death of the E5058 ∆rfaH mutant after air sac infection

challenge
acceptableECOLX:A0A152UJI2Cherylrood, Team Voldemort2017-03-25 23:47:29 CDTGO:0009405 pathogenesis (P)PMID:25461694ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4 Colonization of the Escherichia coli (E058 strain) ∆rstA mutant was significant lower than those of the wild-type E058 strain in the internal organs of chickens.

challenge
acceptableECOLX:Q6X972Cherylrood, Team Voldemort2017-03-25 23:42:40 CDTGO:0009405 pathogenesis (P)PMID:20974831ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 4. The Escherichia coli (DE205M) ∆ibeA mutant-infected ducks had significantly lower bacteria loads isolated from lungs and brains of ducks compared to those infected with wild type E. coli (DE205B).

challenge
acceptableECOLX:F5AP03Cherylrood, Team Voldemort2017-03-25 23:37:04 CDTGO:0009405 pathogenesis (P)PMID:22565007ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 3. Recovered bacteria in the brains of infected ducks was significantly reduced for the ∆ibeB mutant strain Escherichia coli DE205B4 compared to wild-type strain DE205B

challenge
acceptableEDWTA:A2TEZ4Cherylrood, Team Voldemort2017-03-24 01:07:42 CDTGO:0009405 pathogenesis (P)PMID:27102497ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4a. In vivo infection study: Turbot (flatfish) were infected with a dose of Edwardsiella tarda TX01, TX01Δfur, or TX01ΔfurC. Plate counts of bacteria recovered from organs of TX01Δfur-infected fish were significantly lower than the TX01-infected fish at 24 and 48 hours post infection.

challenge
acceptableEDWTA:A2TEZ4Cherylrood, Team Voldemort2017-03-19 17:41:13 CDTGO:1900705 negative regulation of siderophore biosynthetic process (P)PMID:27102497ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 2 Chromoazurol S (CAS) assay compares siderophore production of Edwardsiella tarda TX01 and TX01Δfur. TX01Δfur (Ferric uptake regulator) mutant had increased siderophore production.

challenge
acceptableEDWTA:A2TEZ4Cherylrood, Team Voldemort2017-03-19 17:38:51 CDTGO:0040010 positive regulation of growth rate (P)PMID:27102497ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 1.

Growth analysis of Edwardsiella tarda TX01 showed faster growth rate than TX01Δfur (ferric uptake regulator) mutant

challenge
updatedbyinstructorNOSS1:Q8YP05Cherylrood, Team Voldemort2017-03-05 15:37:35 CSTGO:0016163 nitrogenase activity (F)PMID:27102494ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4.

Nitrogenase activity comparing wild type, Alkylhydroperoxide reductase(ahpC) An + ahpC and AnΔahpC strains of Anabaena species (PCC7120) under control and methyl viologen stress.

challenge
updatedbyinstructorPORGN:A0A0E2LMN8Seannash, Team Voldemort2017-03-05 15:27:25 CSTGO:0044011 single-species biofilm formation on inanimate substrate (P)PMID:17020544ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5.

Biofilm phenotype analysis by CLSM shows Porphyromonas gingivalis (strain 381) formed more abundant biofilms with bacterial cell clusters than mutant uspA* (CW301). *Universal Stress Protein

challenge
updatedbyinstructorNOSS1:Q8YP05Cherylrood, Team Voldemort2017-02-26 23:00:29 CSTGO:1905157 positive regulation of photosynthesis (P)PMID:27102494ECO:0000315 mutant phenotype evidence used in manual assertion

Table 1.

Alkylhydroperoxide reductase (ahpC) in Anabaena species (PCC7120) Table comparing PS I, PS II activity and respiration in wild type, AnΔahpC and An + ahpC.

challenge
updatedbyinstructorSALTY:USPACherylrood, Team Voldemort2017-02-26 20:54:27 CSTGO:0009405 pathogenesis (P)PMID:17081727ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 7A At a dosage of 10^6 Salmonella typhimurium C5, M29 (uspA mutant) was significantly less virulent compared to the wild type

challenge
updatedbyinstructorACIBA:C9D9L2Cherylrood, Team Voldemort2017-02-17 15:22:15 CSTGO:0009405 pathogenesis (P)PMID:25466824ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 6

These two graphs showed that both Wild-type and overexpressed uspA (Universal Stress Protein A) contributed to Acinetobacter baumannii (ATCC 17978) pneumonia pathogenesis and lethality in sepsis.

challenge

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Pages in category "Team Voldemort"

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