Category:Team Splice splice baby

Inhibitory effect on pre-mRNA splicing process.

Provides regulation for the process of alternative splicing through interacting with spliceosome proteins.

Provides regulation during the process of neurogenesis and mitotic spindle regulation.

Provides regulation of negative regulation of the splicing of exons during mRNA splicing.

Provides regulation of calcium ion uptake activity.

Provides phosphorylation inhibition.

Fulfills roles as both activator and repressor. provides upregulation during transcription of RNA.

Provides trans-splicing, also involved in RNA adherence.

Provides stabilization in sarcolemma formation, mRNA splicing dysfunction creates muscular dystophy.

Following transfection of HEK293 cells with RBM10-EGFP WT, the fusion protein was readily detected by western blot analysis (Fig. 4b) and predominantly localized to the nucleus (Fig. 4c)

Involved in process of transcription, E-box adherence and immunoglobulin adherence.

Microtubule production, also involved in cytokinesis and endocytosis.

Expression of lipoprotein receptors during inflammatory cascade.

Controls G-protein receptor expression during mRNA splicing.

Metal ion adherence during RNA splicing, dysfunction of this causes the initiation of Retinitis pigmentosa.

Acts a pre-mRNA splicing factor in the nucleus.

Fig 3, human Tdrd6.

Maintains potassium uptake, dysfunction causes disease.

Maintains homeostasis of purine/pyrimidine nucleotides located intracellularly.

Figure 3. "Surprisingly, in olfactory bulbs (Figures 3(a)(A), 3(a)(B), and 3(b)(A)), high levels of coilin were noted in the highly DAPI-dense nuclear regions surrounding single CBs (Figures 3(b)(B)–3(b)(D)). This nuclear distribution pattern of coilin was observed in individual nuclei of the granular layer of the OBs in adult brain (Figures 3(b)(A)–3(b)(C); see magnification in Figure 3(b)(D) and quantification in Figure 3(b)(E))." Mouse, coilin.

Effects RNA splicing in myoblast formation, causes dysfunction in muscle contraction. More commonly associated with Duchenne Muscular Dystrophy.

Attaches to double stranded and single stranded DNA, and helps maintain DNA fidelity to create mRNA.

Supplies copper ions to proteins that require the usage of copper ions. Copper ions are supplied through the Trans-Golgi network. Malfunction causes abnormal RNA splicing.

Controls all mechanisms of RNA splicing, which includes mRNA splicing through the splicesome, RNA splicing through transesterification mechanisms, and mRNA processing.

Activated in response to cellular stress that would cause damage to DNA and formation and splicing mRNA.

tRNAs acts a catalysis of dihydrouridine, during translation.

Regulates the function of hepatocyte growth signaling and regulation.

Functions during pre-replication before mRNA splicing occurs.

p32 assists in immune system response modulation, apoptotic regulation and expression in addition to regulating pre-mRNA splicing functions.

SMU1 acts as suppressor to mec-8 and as a suppressor to unc-52.