GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|Status||Page||User||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|HUMAN:VNN1||Bonifera, MichSt14A 27||2014-04-06 17:27:17 CDT||GO:0017159 pantetheine hydrolase activity (F)||PMID:24140347||ECO:0000315 mutant phenotype evidence used in manual assertion|
In the article, Figure 2 shows that wild-type cells have much higher pantetheinase activity compared to mutant cells with Vnn1 knocked out, indicating that Vnn1 has pantetheine hydrolase activity.
|HUMAN:PHOP1||Bonifera, MichSt14A 27||2014-04-06 17:23:32 CDT||GO:0044606 phosphocholine hydrolase activity (F)||PMID:24225136||ECO:0000314 direct assay evidence used in manual assertion|
Figure 1 shows some of the human phosphocholine hydrolase enzymes and the correlation between various cytotoxic t cell lines and apoptosis. Without the phosphocholine hydrolase activity of these enzymes, apoptosis wouldn't be induced and there would be no reduction in percent survival.
|CHLRE:A8IC80||Bonifera, MichSt14A 27||2014-04-06 17:02:31 CDT||GO:0047714 galactolipase activity (F)||PMID:23161887||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 1 shows the accumulation of triacylglycerides in both wild type and mutants. In the mutant knockout strain, we see a much lower percentage of triacylglycerols in the total fatty acid content. This indicates that the protein has galactolipase function that, in this case, is important following nitrogen deprivation.
|HUMAN:CXB2||Bonifera, MichSt14A 27||2014-04-06 16:45:33 CDT||GO:0005243 gap junction channel activity (F)||PMID:24624091||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 1 shows a much higher concentration of ions in components of the inner human ear for the mutant phenotype. However, in the wild type, with the functional Cx26, you see a much smaller ion concentration, indicating gap junction channel activity.
|YEAST:BAP2||Bonifera, MichSt14A 27||2014-04-06 16:43:26 CDT||GO:1990122 leucine import into cell (P)||PMID:24699373||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 1A shows the OD concentrations of leucine from a cell for both wild types strains and for mutant strains. The wild type, with a BAP2 gene, has the highest OD of leucine and the mutants have decreased ODs.
|PSEAE:Q9I4H4||Bonifera, MichSt14A 27||2014-04-05 11:50:03 CDT||GO:0006075 (1->3)-beta-D-glucan biosynthetic process (P)||PMID:23637868||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 1A shows the different growth patterns shown in both the ndvB mutant and also in the wild type. Clearly, the wild type exhibits a higher growth capability due to the beta-glucan biosynthesis and sequestration of antibiotics in the periplasm.
What do the icons mean in the status column?
Pages in category "MichSt14A 27"
This category contains only the following page.