name: sumoylated E2 ligase complex
The contents of this box are automatically generated. You can help by adding information to the "Notes"
def: "A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase." [GOC:bhm, PMID:18691969]
comment: An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay).
is_a: GO:0032991 ! protein-containing complex
Gene Ontology Home
See Help:References for how to manage references in GONUTS.
Pages in category "GO:1990356 ! sumoylated E2 ligase complex"
The following 2 pages are in this category, out of 2 total.
Jump to pages starting with: C P